Patents Assigned to IP2IPO Innovations Limited
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Publication number: 20240122714Abstract: An implant system for implantation at a joint. The implant system includes an implant device with a body portion having first and second ends, and a first elongate member, extending from the first or second end of the body portion. The implant system has a corresponding fixation device with at least one latching element. The first elongate member has at least one cooperating element capable of cooperating with the at least one latching element of the fixation device in use.Type: ApplicationFiled: August 7, 2023Publication date: April 18, 2024Applicant: IP2IPO Innovations LimitedInventors: Andrew Arthur Amis, Justin Peter Cobb, Anthony Michael James Bull, Sarat Babu
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Patent number: 11945799Abstract: The invention provides compounds of formula I, wherein the substituents are as set out in further detail in the specification. The compounds are potent inhibitors of GCN2 and they have excellent pharmacokinetic properties. The compounds are useful for the treatment or prevention of a variety of conditions, particularly cancer. The invention further provides pharmaceutical compositions comprising the compounds of the invention and uses of the compounds and the compositions.Type: GrantFiled: March 28, 2023Date of Patent: April 2, 2024Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Gavin Whitlock, Matthew Fuchter
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Patent number: 11813045Abstract: An implantable intravascular pressure sensor comprising a first transducer arranged to provide a pressure dependent signal in response to alternating electrical signals of a first frequency band, a second transducer arranged to provide a reference signal in response to alternating electrical signals of a second frequency band different from the first frequency band and an antenna coupling for sending and receiving said signals.Type: GrantFiled: September 20, 2017Date of Patent: November 14, 2023Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Mohammad Reza Bahmanyar, Christopher Neil McLeod, Olive H Murphy
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Patent number: 11800987Abstract: An implantable intravascular device for deployment inside a human or animal, the apparatus comprising a body of crystalline material and a membrane of crystalline material fixed to the body by a hermetic bond an assembly of components carried on said crystalline material and arranged for responding to electrical signals wherein the body and the membrane at least partially encapsulate the assembly.Type: GrantFiled: September 20, 2017Date of Patent: October 31, 2023Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Mohammad Reza Bahmanyar, Christopher Neil McLeod
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Publication number: 20230271939Abstract: The invention provides compounds of formula I, wherein the substituents are as set out in further detail in the specification. The compounds are potent inhibitors of GCN2 and they have excellent pharmacokinetic properties. The compounds are useful for the treatment or prevention of a variety of conditions, particularly cancer. The invention further provides pharmaceutical compositions comprising the compounds of the invention and uses of the compounds and the compositions.Type: ApplicationFiled: June 9, 2021Publication date: August 31, 2023Applicant: IP2IPO INNOVATIONS LIMITEDInventors: Gavin WHITLOCK, Matthew FUCHTER
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Patent number: 11725066Abstract: The present invention relates to a process for extracting oxidised metal pollutants from treated cellulosic or lignocellulosic biomass to recover the metal. The treatment also generates a cellulosic or lignocellulosic biomass which can to be used as a feedstock for biofuel, for making cellulose containing materials, and provides a source of other renewable chemicals.Type: GrantFiled: April 2, 2021Date of Patent: August 15, 2023Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Jason Hallett, Paul Fennell, Florence Gschwend, Agnieszka Brandt-Talbot, Geoffrey Kelsall
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Publication number: 20230250082Abstract: The invention provides compounds of formula I, wherein the substituents are as set out in further detail in the specification. The compounds are potent inhibitors of GCN2 and they have excellent pharmacokinetic properties. The compounds are useful for the treatment or prevention of a variety of conditions, particularly cancer. The invention further provides pharmaceutical compositions comprising the compounds of the invention and uses of the compounds and the compositions.Type: ApplicationFiled: March 28, 2023Publication date: August 10, 2023Applicant: IP2IPO INNOVATIONS LIMITEDInventors: Gavin WHITLOCK, Matthew FUCHTER
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Patent number: 11696680Abstract: An ear examination tool comprises a handle and a speculum mount coupled to the handle. The speculum mount is configured for retaining a disposable speculum. An spacing element is coupled to the handle and extends from the handle. A smartphone mount is coupled to the spacing element, and the spacing element is configured to maintain an optical separation distance between the speculum mount and the smartphone mount. The tool enables a clear view of the ear canal while allowing access by, and manipulation of, a microsuction tool being inserted into the ear canal. The extensive optical and data processing functionality of a “smartphone” can be integrated at low cost into an ear examination tool to provide a substantially improved piece of equipment for assisting in ear examination and microsuction of the ear.Type: GrantFiled: December 11, 2018Date of Patent: July 11, 2023Assignee: IP2IPO Innovations LimitedInventors: Daniel Stuart Elson, Miroslav Janatka, Taranjit Singh Tatla, Arvind Singh, Savram Krishan Ramdoo
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Patent number: 11591380Abstract: The invention provides novel compounds which are peptide hormone analogues, and which are useful in treating disorders such as diabetes and obesity. The compounds of the general sequence recited in the specification possess a tailored profile with regards to potency properties at the glucagon and GLP-1 receptors. With regard to in vivo properties, administration of example peptides of the invention has been shown, in animal models, to result in increased weight loss.Type: GrantFiled: December 4, 2018Date of Patent: February 28, 2023Assignee: IP2IPO INNOVATIONS LIMITEDInventor: Stephen Robert Bloom
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Patent number: 11566029Abstract: Certain pyrazolo[1,5-a]pyrimidine-5,7-diamine compounds that inhibit cycline dependent kinase (CDK) (e.g., CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, CDK10, CDK11, CDK12, CDK13, etc.) are disclosed. Pharmaceutical compositions comprising these compounds, and the use of these compounds and compositions to inhibit CDK; to treat disorders associated with CDK such as those arising from an inappropriate activity, mutation, overexpression, or upstream pathway activation of CDK; or disorders that are ameliorated by the inhibition of CDK; proliferative disorders; cancer; viral infections; neurodegenerative disorders; ischaemia; renal diseases; and cardiovascular disorders are also disclosed. Optionally, the treatment further comprises simultaneous or sequential treatment with a further active agent, e.g., an aromatase inhibitor, an anti-estrogen, a Her2 blocker, a cytotoxic chemotherapeutic agent, etc.Type: GrantFiled: February 15, 2021Date of Patent: January 31, 2023Assignees: IP2IPO Innovations Limited, Emory University, Cancer Research Technology LimitedInventors: Alexander Bondke, Sebastian Kroll, Anthony Barrett, Matthew Fuchter, Brian Slafer, Simak Ali, Charles Coombes, James Patrick Snyder
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Publication number: 20230014135Abstract: Apparatus for locating an attachment position for a reconstructed anterior cruciate ligament on an attachment surface of a bone comprises locating means 51, 61 arranged to locate at least one reference surface 4 of the bone and guide means 53, 54 arranged to define the attachment position in two dimensions on the attachment surface relative to the reference surface.Type: ApplicationFiled: September 27, 2022Publication date: January 19, 2023Applicant: IP2IPO INNOVATIONS LIMITEDInventors: Andrew AMIS, Andrew EDWARDS
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Patent number: 11421012Abstract: Analogues of PYY differing from native human PYY by substitution of Ser23 with Ala23, Glu23, Lys23, Gln23 or AIB23. Further optional features include substitutions at further positions, loss of the Tyr1 residue of native human PYY and amidation of the C-terminus. Suitable for use as pharmaceuticals for treating and preventing disorders, in particular diabetes and obesity.Type: GrantFiled: December 4, 2018Date of Patent: August 23, 2022Assignee: IP2IPO INNOVATIONS LIMITEDInventor: Stephen Robert Bloom
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Patent number: 11411171Abstract: The disclosed non-volatile memory cell comprises a storage layer of an electrically insulating polarisable material in which data is recordable as a direction of electric polarisation, preferably of ferroelectric material, arranged between a magnetically frustrated layer, preferably of Mn-based antiperovskite piezomagnetic material and a conduction electrode. The magnetically frustrated layer has a different change in density of states relative to the conduction electrode in response to a change in electric polarisation of the storage layer, such that an electron or spin tunnelling resistance across the storage layer is dependent on the direction of electric polarisation.Type: GrantFiled: August 6, 2019Date of Patent: August 9, 2022Assignee: IP2IPO Innovations LimitedInventors: Jan Zemen, Bin Zou, Andrei Mihai
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Patent number: 11396010Abstract: A catalytic convertor comprising a substrate body (100) arranged within the catalytic convertor such that a principal flow of fluid through the catalytic convertor flows along a surface (101) of the substrate body, wherein said surface (101) has a plurality of openings (210) to micro-channels that extend away from said surface (101); and at least a portion of the surface (101) of the substrate body (100) comprises a catalytically active material, wherein the substrate body (100) is in the form of: a pellet; a sheet; solid elongate bodies; solid rods; a solid body having a plurality of bores; a non-tubular elongate body; a non-hollow body; a sheet curved in the form or a spiral; or a combination thereof.Type: GrantFiled: April 27, 2020Date of Patent: July 26, 2022Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Benjamin Francis Knatchbull Kingsbury, Kang Li, Zhentao Wu
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Patent number: 11387092Abstract: The disclosure provides a thermal desorption (TD) tube sampler. The sampler comprises a first connector configured to reversibly connect to a TD tube containing a sample, and a second connector configured to couple to a direct injection mass spectrometer. The TD tube sampler is configured to desorb a sample in a TD tube connected thereto, and feed the desorbed sample from the TD tube to a direct injection mass spectrometer such that the desorbed sample does not pass through a cold trap.Type: GrantFiled: July 2, 2019Date of Patent: July 12, 2022Assignee: IP2IPO INNOVATIONS LIMITEDInventors: George Hanna, Andrea Romano
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Patent number: 11375956Abstract: An implantable intravascular anchor for supporting a device inside a vascular lumen, the anchor comprising a first part configured to expand when extending from a catheter, and to collapse upon retraction into said catheter; a second part for supporting the device in the lumen and a third part, proximal to the first part, and configured so that, upon release from the catheter, it expands in width to engage an interior wall of the lumen and is adapted for securing the anchor against axial movement along the lumen.Type: GrantFiled: September 21, 2017Date of Patent: July 5, 2022Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Mohammad Reza Bahmanyar, Christopher Neil McLeod
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Publication number: 20220173422Abstract: A method of operating a flow cell. The method comprises providing a flow cell suitable for generating electrical power from hydrogen and a metal electrolyte. Said flow cell comprises a precipitate of metal oxi and said metal oxide comprises vanadium or manganese. The method further comprises electrochemically generating a redox active precipitate removal species from a precursor species, wherein said redox active precipitate removal species is capable of converting said metal oxide. The method further comprises exposing said metal oxide to said redox active precipitate removal species to effect conversion of the metal oxide.Type: ApplicationFiled: February 27, 2020Publication date: June 2, 2022Applicant: IP2IPO Innovations LimitedInventors: Anthony Kucernak, Javier Rubio-Garcia
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Patent number: 11324409Abstract: An implantable device for sensing intravascular pressure, the device comprising a bulk acoustic wave (BAW) resonator arranged to be deflected by changes in intravascular fluid pressure to provide a pressure dependent sensing signal and an acoustic reflector arranged to separate the BAW resonator from the intravascular fluid and to mediate pressure from the intravascular fluid to the BAW resonator wherein the acoustic reflector comprises a layer structure arranged to provide a series of transitions in acoustic impedance between the intravascular fluid and the BAW resonator.Type: GrantFiled: November 2, 2017Date of Patent: May 10, 2022Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Mohammad Reza Bahmanyar, Christopher Neil McLeod
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Patent number: 11248230Abstract: The present invention related to identification of therapeutic agents of the treatment, diagnosis, and prevention of pulmonary hypertension.Type: GrantFiled: June 5, 2019Date of Patent: February 15, 2022Assignee: IP2IPO Innovations LimitedInventors: Eduardo Oliver-Perez, Lan Zhao, Martin Wilkins, Tim Aitman
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Patent number: RE48970Abstract: A surface or bulk acoustic wave device can be implanted in or worn on a human or animal body to monitor various parameters thereof. The device comprises a pair of interdigitated transducers spaced apart over the surface of a piezo-electric substrate that is exposed to the parameter to be monitored. The device is interrogated by a radio-frequency signal being supplied to one of the transducers and detected after reflection by the other transducer. The parameter is measured by comparison of the supplied and received signals.Type: GrantFiled: September 19, 2019Date of Patent: March 15, 2022Assignee: IP2IPO INNOVATIONS LIMITEDInventors: Christofer Toumazou, Christopher Neil McLeod, Glenn Noel Robert Vandevoorde