Patents Assigned to IPROTEOS S,L,
  • 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives
    Patent number: 10611727
    Abstract: The present invention relates to 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives having pharmacological activity formula (I) to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of a cognitive disorder.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: April 7, 2020
    Assignees: UNIVERSITAT DE BARCELONA, FUNACIÓ INSTITUT DE RECERCA BIOMÉDICA, IPROTEOS S.L.
    Inventors: Ernest Giralt Lledó, Teresa Tarragó Clua, Roger Prades Cosano, Soledad Royo Gracia
  • Gelatinase inhibitors and use thereof
    Patent number: 10414797
    Abstract: New gelatinase inhibitors, processes for their preparation, pharmaceutical compositions comprising them, and their use in therapy and/or prophylaxis of conditions wherein inhibition of gelatinases is useful such as epilepsy, schizophrenia, Alzheimer disease, autism (in particular associated to fragile X syndrome), mental retardation, mood disorders such as bipolar disorders, depression, vascular diseases such as ischemic stroke and atherosclerosis, inflammatory diseases such as multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease, drug addiction, neuropathic pain, lung diseases such as asthma and chronic obstructive pulmonary disease, cancer and sepsis.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: September 17, 2019
    Assignee: Iproteos S.L
    Inventors: Roger Prades Cosano, Jésus Seco Moral, María Teresa Tarragó Clua
  • 1-[1-(BENZOYL)-PYRROLIDINE-2-CARBONYL]-PYRROLIDINE-2-CARBONITRILE DERIVATIVES
    Publication number: 20190084927
    Abstract: The present invention relates to 1-[1-(benzoyl )-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives having pharmacological activity formula (I) to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of a cognitive disorder.
    Type: Application
    Filed: September 26, 2018
    Publication date: March 21, 2019
    Applicants: UNIVERSITAT DE BARCELONA, FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA), IPROTEOS S.L.
    Inventors: Ernest Giralt Lledó, Teresa Tarragó Clua, Roger Prades Cosano, Soledad Royo Gracia
  • 1- [1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives
    Patent number: 10125097
    Abstract: The present invention relates to 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives having pharmacological activity to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of a cognitive disorder.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: November 13, 2018
    Assignees: UNIVERSITAT DE BARCELONA, FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA), IPROTEOS S.L.
    Inventors: Ernest Giralt Lledó, Teresa Tarragó Clua, Roger Prades Cosano, Soledad Royo Gracia
  • GELATINASE INHIBITORS AND USE THEREOF
    Publication number: 20180319839
    Abstract: New gelatinase inhibitors, processes for their preparation, pharmaceutical compositions comprising them, and their use in therapy and/or prophylaxis of conditions wherein inhibition of gelatinases is useful such as epilepsy, schizophrenia, Alzheimer disease, autism (in particular associated to fragile X syndrome), mental retardation, mood disorders such as bipolar disorders, depression, vascular diseases such as ischemic stroke and atherosclerosis, inflammatory diseases such as multiple sclerosis, rheumatoid arthritis and inflammatory bowel disease, drug addiction, neuropathic pain, lung diseases such as asthma and chronic obstructive pulmonary disease, cancer and sepsis.
    Type: Application
    Filed: November 15, 2016
    Publication date: November 8, 2018
    Applicant: Iproteos S.L
    Inventors: Roger Prades Cosano, Jésus Seco Moral, María Teresa Tarragó Clua
  • 1-[1-(BENZOYL)-PYRROLIDINE-2-CARBONYL]-PYRROLIDINE-2-CARBONITRILE DERIVATIVES
    Publication number: 20160168088
    Abstract: The present invention relates to 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives having pharmacological activity to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of a cognitive disorder.
    Type: Application
    Filed: November 11, 2013
    Publication date: June 16, 2016
    Applicant: IPROTEOS S,L,
    Inventors: Ernest GIRALT LLEDÓ, Teresa TARRAGÓ CLUA, Roger PRADES COSANO, Soledad ROYO GRACIA