Patents Assigned to Ire-Medgenix S.A.
  • Vitamin D derivatives: therapeutic applications and applications to assays of metabolites of vitamin D
    Patent number: 5232836
    Abstract: Vitamin D derivatives corresponding to the following formula I ##STR1## in which R.sub.1 denotes a substituted alkyl group having 1 to 15 carbon atoms, in particular the side chains of vitamin D.sub.2 (C.sup.20 to C.sup.28) or D.sub.3 (C.sup.20 to C.sup.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: August 3, 1993
    Assignee: Ire-Medgenix S.A.
    Inventors: Roger Bouillon, Pierre J. De Clerco, Pierre Eliard, Maurits Vanderwalle
  • Assay of monokines
    Patent number: 5128270
    Abstract: The invention relates to assays of a monokine in a biological fluid, in particular in a blood sample, in particular of TNF or of IL-1. According to the present invention, the monokine in the serum or plasma obtained from whole blood stimulated with a mitogenic agent is assayed prior to any separation between the plasma (or serum) and the blood cells. According to another subject of the invention, the monokine is assayed in the case of an immunometric assay employing an oligoclonal system, consisting of several different monoclonal antibodies adsorbed on a solid phase and a non-adsorbed labeled antibody.The invention also relates to immunoassay kits.
    Type: Grant
    Filed: January 6, 1989
    Date of Patent: July 7, 1992
    Assignee: Ire-Medgenix S.A.
    Inventors: Dominique Delacroix, Donat De Groote, Paul Franchimont, Philippe Gysen, Aimee Reuter, Isabelle Dehart
  • Vitamin D derivatives: therapeutic applications and applications to assays of metabolities of vitamin D
    Patent number: 5093519
    Abstract: Vitamin D derivatives corresponding to the following formula I ##STR1## in which R.sub.1 denotes a substituted alkyl group having 1 to 15 carbon atoms, in particular the side chains of vitamin D.sub.2 (C.sup.20 to C.sup.28) or D.sub.3 (C.sup.20 to C.sup.
    Type: Grant
    Filed: May 1, 1989
    Date of Patent: March 3, 1992
    Assignee: Ire-Medgenix S.A.
    Inventors: Roger Bouillon, Pierre J. De Clercq, Pierre Eliard, Maurits Vandewalle