Patents Assigned to IRM LLC, a Delaware LLC
  • Pyrrolidones with anti-HIV activity
    Publication number: 20040157859
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Application
    Filed: October 21, 2003
    Publication date: August 12, 2004
    Applicant: IRM LLC, a Delaware LLC
    Inventors: Baogen Wu, Yun He, Truc Ngyuen, Kelli L. Kuhen, David Archer Ellis, Tao Jiang, Xiaohui Xe, Kunyong Yang, Badry Bursulaya
  • Quinolones with anti-HIV activity
    Publication number: 20040152719
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Application
    Filed: October 21, 2003
    Publication date: August 5, 2004
    Applicant: IRM LLC, a Delaware LLC
    Inventors: Yun He, David Archer Ellis, Beth Marie Anaclerio, Kelli L. Kuhen, Baogen Wu, Tao Jiang
  • Oxindoles with anti-HIV activity
    Publication number: 20040152755
    Abstract: The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
    Type: Application
    Filed: October 21, 2003
    Publication date: August 5, 2004
    Applicant: IRM LLC, a Delaware LLC
    Inventors: Yun He, Tao Jiang, Kelli L. Kuhen, David Archer Ellis, Baogen Wu, Tom Yao-Hsiang Wu, Badry Bursulaya
  • Solution phase synthesis of arylbenzoxazoles
    Publication number: 20030148387
    Abstract: This invention provides methods for the solution-phase synthesis of arylbenzoxazoles. The methods involve condensation of aminophenols with benzaldehydes to form a Schiff base. The Schiff base is then induced to undergo oxidative cyclization in the presence of DDQ. The resulting arylbenzoxazoles can be separated from the reduced DDQ byproduct by treatment of reaction mixture with a strongly basic ion exchange resin.
    Type: Application
    Filed: November 19, 2002
    Publication date: August 7, 2003
    Applicant: IRM LLC, a Delaware LLC
    Inventors: Junbiao Chang, Shifeng Pan