Patents Assigned to Irvine Biomedical Inc.
  • Patent number: 6217576
    Abstract: An improved catheter system and methods for ablating cardiac tissues via a steerable ablation catheter having a liquid-permeable shaft, a liquid-permeable electrode, or a distal opening at its tip section with fluid infusion and irrigation for ablating intracardiac tissues by applying radiofrequency energy along with irrigated fluid in a pulmonary vein resulting in a controlled lesion for treating focal atrial fibrillation.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: April 17, 2001
    Assignee: Irvine Biomedical Inc.
    Inventors: Hosheng Tu, Weng-Kwen Raymond Chia, Cary Hata
  • Patent number: 6033402
    Abstract: An improved lead extraction system using a retractable inner catheter having an electrode means comprising memory-shaped Nitinol sheet members and a RF current generator to raise the temperature to above the transitional shape-change temperature of the Nitinol with a sharp cutting edge. The lead extraction system is useful for the extraction and the removal of unwanted lead by a minimal invasive procedure. In another embodiment, fluid infusion and irrigation means at its distal tip section and an electrode means for loosening the target scar tissue by applying radiofrequency energy and cooled fluid to the said electrode and its contacted tissue.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: March 7, 2000
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Cary Hata
  • Patent number: 6033403
    Abstract: An improved catheter system having an electrode means at its tip section capable of delivering a long continuous linear lesion in tissues of a patient. A catheter system suitable for radiofrequency ablation of cardiac tissues comprising an electrode means mounted on the distal tip section of the catheter shaft, the electrode means having a wire and a plurality of ring electrodes, the wire having a wire core section, a wire distal end and a wire proximal end, wherein a first ring electrode is secured to the wire distal end and a second ring electrode is secured to the wire proximal end. The catheter system also comprises an external RF current generator, wherein a RF current is delivered to the electrode means.
    Type: Grant
    Filed: October 8, 1998
    Date of Patent: March 7, 2000
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Cary Hata
  • Patent number: 6029091
    Abstract: A catheter system comprising a delivery catheter and an inner catheter, wherein the inner catheter is deployable and has a plurality of electrodes on the lattices of a trellis fixture. During a deployed state, the trellis fixture is fully extended to have a series of electrodes on a two-dimensional plane for mapping and/or ablation purposes.
    Type: Grant
    Filed: July 9, 1998
    Date of Patent: February 22, 2000
    Assignee: Irvine Biomedical, Inc.
    Inventors: Alan de la Rama, Nadir Saoudi
  • Patent number: 6016437
    Abstract: A cardiovascular catheter probe system suitable for electrophysiology mapping and radiofrequency ablation of cardiac tissue comprises a plurality of catheter shafts having a proximal end, a distal handle, and a lumen extending therebetween, wherein a distal portion of the shaft is deflectable and inflatable; the wavy soft distal section is inflatable to conform intimately to the irregular intracardiac tissue surface, wherein conducting electrodes are secured on the hills of said inflatable wavy soft shaft.
    Type: Grant
    Filed: August 21, 1998
    Date of Patent: January 18, 2000
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Chi-Wu James Chang
  • Patent number: 6006123
    Abstract: A method for positioning an electrode catheter system having safety means at its distal section within a heart chamber comprises percutaneously introducing the distal end of a catheter through an artery or vein to the heart chamber. Once the catheter tip is at the desired location, the connector of the handle at the proximal end is connected to an EKG monitor. And the electrical signal from the electrodes on the distal section can be transmitted to the exterior EKG monitor for cardiac mapping. Alternately, the radio frequency current can be supplied to one or more of the electrodes on the distal section once an intimate contact with a tissue is achieved using the catheter of this invention.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: December 21, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Tho Hoang Nguyen, Hosheng Tu
  • Patent number: 6001095
    Abstract: A catheter system suitable for electrophysiology mapping and radiofrequency ablation of cardiac tissue comprises a catheter shaft having a distal end, a proximal handle, and at least a lumen extending therebetween, wherein a distal section of the shaft is either a fixed curve type or a deflectable type; and safety means being provided to maintain the integrity of the catheter by holding the long tip electrode in place, wherein the safety means is a long tip electrode with an extended flexible stem having at least one open groove or slot on the stem.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: December 14, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Alan de la Rama, Weng-Kwen Raymond Chia, Hosheng Tu
  • Patent number: 5992418
    Abstract: The method for using a catheter system suitable for electrophysiology mapping and radiofrequency ablation of cardiac tissue comprises a catheter shaft having a distal end, a proximal handle, and at least one lumen extending therebetween, wherein a distal section of the shaft is either a fixed curve type or a deflectable type; and a safety means provided to maintain the integrity of the catheter, by anchoring the tip electrode in place. In one embodiment, the safety means is a tip electrode with safety anchoring pins. In another embodiment, the safety means is a long tip electrode with an extended flexible stem having at least one open slot or groove or groove on the stem.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: November 30, 1999
    Assignee: Irvine Biomedical , Inc.
    Inventors: Alan de la Rama, Weng-Kwen Raymond Chia, Hosheng Tu
  • Patent number: 5980515
    Abstract: An improved lead extraction system using a rotatable hole saw electrode with a sharp cutting edge that is useful for the extraction and the removal of unwanted lead by a minimal invasive procedure. A lead extraction system suitable for radiofrequency ablation of scar tissues surrounding the implanted lead, is comprised of an outer catheter sheath and an inner delivery catheter having a distal end, a proximal end and at least one lumen extending therebetween, wherein a locking stylet is provided. In one embodiment, the lead extraction system has fluid infusion and irrigation means at its distal tip section and a rotatable hole saw electrode for loosening the target scar tissue by applying radiofrequency energy and cooled fluid to the said electrode and its contacted tissue.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: November 9, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventor: Hosheng Tu
  • Patent number: 5971968
    Abstract: A catheter probe and methods for contrast media delivering comprising localized contrast media irrigation means for providing contrast media to the distal tip section, wherein the contrast media irrigation means is externally connected to a contrast media supply source; and shaft opening means for venting the contrast media out of the shaft distal end at an angle in relation to an axial reference line for optimal x-ray imaging, wherein the shaft opening means is connected to and in communication with a conduit of the contrast media irrigation means, and wherein the shaft opening means comprises at least one opening at an angle in relation to an axial reference line.
    Type: Grant
    Filed: April 8, 1999
    Date of Patent: October 26, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Cary Hata, Alan de la Rama
  • Patent number: 5954649
    Abstract: An improved catheter system having ultrasound locating capabilities comprising a locator catheter and an ultrasound receiver catheter resulting in an effective electrophysiology procedure without undesired side effects of using a conventional x-ray imaging system.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: September 21, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Weng-Kwen Raymond Chia, Hosheng Tu
  • Patent number: 5954719
    Abstract: A catheter-based system for operating a RF ablation generator comprising a RF splitter for delivering RF energy to a plurality of electrodes; a low-pass filter located between the RF splitter and an external EKG monitor for displaying real-time signal to said EKG monitor; and a software program having temperature data input from a plurality of temperature sensors and signal output capability, wherein the software program sends out signals to the RF splitter being adapted to control the RF energy output to each electrode.
    Type: Grant
    Filed: March 23, 1998
    Date of Patent: September 21, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Peter Cheng Chen, Tho Hoang Nguyen
  • Patent number: 5951471
    Abstract: A catheter-based method for coronary sinus mapping, pacing, and ablation, wherein a flexible electrode catheter, having a tip electrode with suspension structure, is pre-shaped to snugly fit into the coronary sinus, so that the tip electrode is positioned into the sinus; the distal section is deflected to expose a predetermined plurality of electrodes; and RF energy is then applied to the coronary sinus tissue through the electrodes to cause activation mapping, and/or ablation.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: September 14, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Alan de la Rama, Hosheng Tu
  • Patent number: 5941845
    Abstract: An improved ablation catheter with at least one multiple-needle electrode can be used in ablating the arrhythmogenic region instead of an arrhythmogenic point of a patient. This catheter is particularly useful for treating the patient with atrial fibrillation (AFib) indications. A catheter suitable for radiofrequency ablation of cardiac tissues comprises a delivery catheter and an inner catheter having a distal section, a distal end, a proximal end and at least one lumen extending therebetween. The ablation catheter has a temperature sensor and a close-loop temperature control. The steerable catheter having at least one multiple-needle electrode is inserted into the chambers of the heart to create a plurality of deep, large, and contiguous lesions by applying radiofrequency energy to said electrode.
    Type: Grant
    Filed: August 5, 1997
    Date of Patent: August 24, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Weng-Kwen Raymond Chia
  • Patent number: 5938659
    Abstract: A method for operating a steerable ablation catheter having at least one multiple-needle electrode at the tip section of an inner catheter within a heart chamber, wherein the ablation catheter including at least one multiple-needle electrode is inserted into a chamber of the heart to create a plurality of deep, large, and contiguous lesions by applying radiofrequency energy and cooled fluid to the electrode.
    Type: Grant
    Filed: April 20, 1998
    Date of Patent: August 17, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Weng-Kwen Raymond Chia
  • Patent number: 5935063
    Abstract: An electrode catheter system suitable for electrophysiology mapping and/or radiofrequency ablation of cardiac tissue comprises a catheter shaft having a distal end, a proximal handle, and at least a lumen extending therebetween, wherein a distal section of the shaft is either a fixed curve or deflectable; and safety restricting means at the very distal end of the catheter shaft being provided to maintain the integrity of the catheter by holding the tip electrode in place from thermal cycling effect.
    Type: Grant
    Filed: October 29, 1997
    Date of Patent: August 10, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventor: Tho Hoang Nguyen
  • Patent number: 5913856
    Abstract: An improved ablation catheter having a distal tip section made of flexible porous plastic material for fluid infusion and irrigation at its electrode comprises a catheter shaft having a distal section and at least one lumen extending therebetween, wherein the catheter is inserted into the chambers of the heart to create deep and large lesions by applying radiofrequency energy along with irrigated fluid to the electrode.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: June 22, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Weng-Kwen Raymond Chia, Hosheng Tu
  • Patent number: 5897554
    Abstract: An electrophysiology catheter suitable for radiofrequency ablation of cardiac tissues comprises a proximal section, a catheter shaft section and a distal section whereby a distal loop electrode having a temperature sensor and a close-loop temperature control. A conducting wire extends through the lumen and is connected to the loop electrode. The steerable catheter having a loop electrode is inserted into the chambers of the heart to create a continuous, non-linear lesion by supplying radiofrequency energy to said conducting wire.
    Type: Grant
    Filed: March 1, 1997
    Date of Patent: April 27, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Weng-Kwen Raymond Chia, Hosheng Tu
  • Patent number: 5893884
    Abstract: An improved catheter system, having at least one rollable electrode at its tip section, can be used in ablating the arrhythmogenic point of a patient. A catheter suitable for radiofrequency ablation of cardiac tissues comprises a catheter shaft having a distal section, a distal end, a proximal end, and at least one lumen extending therebetween, wherein at least a rollable electrode is disposed at the tip section of the said catheter. In one embodiment, the ablation catheter has a temperature sensor and a close-loop temperature control mechanism. In another embodiment, the ablation catheter has fluid infusion and irrigation means at its distal tip section for creating a deep and large lesion by applying radiofrequency energy and cooled fluid to the said electrode.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: April 13, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventor: Hosheng Tu
  • Patent number: 5891138
    Abstract: A catheter system comprising a delivery catheter with distal and proximal ends; a handle attached to the proximal end of the delivery catheter; the delivery catheter having an electrode deployment means where said electrode deployment means includes a retractable tip section comprising a plurality of deployable parallel electrodes. The tip section has a non-deployed state when it is positioned in the delivery catheter. On the other hand, the tip section has a distended deployed state when it is advanced out of the distal end of said delivery catheter; wherein the deployed electrodes on the tip section has a preformed shape in a parallel manner. This catheter is particularly useful for treating the patient having tachycardia as a result of its more effective electrodes arrangement for intimate tissue contact.
    Type: Grant
    Filed: August 11, 1997
    Date of Patent: April 6, 1999
    Assignee: Irvine Biomedical, Inc.
    Inventors: Hosheng Tu, Weng-Kwen Raymond Chia