Patents Assigned to IS INVESTMENTS LLC
  • Patent number: 11903679
    Abstract: A robotic system includes retrieval of a priori stimulus based on an input that indicates a current health state and a target health state of a user. A set of test stimuli specific for the user is determined and a stimulus device is controlled to provide the set of test stimuli to the user. A first set of responses within the body of the user and a second set of responses discernible on the body of the user are determined, and a set of stimulus parameters for the stimulus device is calibrated based on the combination of the first set of responses, the second set of responses, the current health state, the target health state, and a trained AI-based system. A new stimulus is applied to a portion of the body of the user that shifts a condition of the user from the current health state towards the target health state.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: February 20, 2024
    Assignee: AR & NS INVESTMENT, LLC
    Inventors: Neda Semsar, Arman Rofougaran
  • Patent number: 11910724
    Abstract: A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: February 20, 2024
    Assignee: ISP INVESTMENTS LLC
    Inventors: Philip John Oths, Shafiq Sahar Wahidi, Petros Gebreselassie, Hani M. Fares
  • Publication number: 20240053499
    Abstract: Methods and computing apparatus for implementing a radiation dosimetry process. An example process may include exposing a first radiation sensitive film to a series of known doses of radiation, measuring a first set of radiation data with a measurement device, and determining a calibration curve. The calibration curve may be determined by selecting Raman spectral ranges based on the first set of radiation data, determining a plurality of band area ratios, and generating the calibration curve based on plotting the band areas and ratios compared to known dose. The radiation dosimetry process then exposes a second radiation sensitive film to an unknown dose of radiation, measures a second set of radiation data for the second radiation sensitive film with the measurement device, and determines a dose exposure level for the second radiation sensitive film by comparing the second set of radiation data with the calibration curve.
    Type: Application
    Filed: December 22, 2021
    Publication date: February 15, 2024
    Applicant: ISP Investments LLC
    Inventors: David K. Hood, Mark Allen DAVIES
  • Patent number: 11899713
    Abstract: A system and method for making categorized music tracks available to end user applications. The tracks may be categorized based on computer-derived rhythm, texture and pitch (RTP) scores for tracks derived from high-level acoustic attributes, which is based on low level data extracted from the tracks. RTP scores are stored in a universal database common to all of the music publishers so that the same track, once RTP scored, does not need to be re-RTP scored by other music publishers. End user applications access an API server to import collections of tracks published by publishers, to create playlists and initiate music streaming. Each end user application is sponsored by a single music publisher so that only tracks capable of being streamed by the music publisher are available to the sponsored end user application.
    Type: Grant
    Filed: January 5, 2023
    Date of Patent: February 13, 2024
    Assignee: APERTURE INVESTMENTS, LLC
    Inventors: Jacquelyn Fuzell-Casey, Skyler Fuzell-Casey
  • Publication number: 20240039924
    Abstract: A blockchain of block entries that can be requested by users from user devices is maintained in a distributed network of nodes. Block entries include a plurality of data portions that are each associated with an access level. A request from an auditor to view one or more data portions of a block entry can includes an access code associated with at least one access level can be evaluated to identify one or more data portions associated with the access level. A customized view of the block entry which includes the one or more data portions associated with the access level can be generated. An artificial intelligence engine can review entries within the distributed ledger, identify earnings information associated with the sales of the commercial inventory, determine tax based on earning information, and pay the tax via fiat or cryptocurrency to government authorities based on earnings information.
    Type: Application
    Filed: July 23, 2023
    Publication date: February 1, 2024
    Applicant: AMERICORP INVESTMENTS LLC
    Inventor: Jordan Simons
  • Patent number: 11887828
    Abstract: Methods are described for detecting or determining the amount of antidepressants and/or antidepressant metabolites in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying antidepressants and/or antidepressant metabolites in a sample.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: January 30, 2024
    Assignee: Quest Diagnostics Investments LLC
    Inventors: Anita Dermartirosian, Edith Shahbol, Karin Thomassian, Shaun Rezaei, Asad Shah
  • Patent number: 11885780
    Abstract: Provided are methods for detecting chromogranin A by mass spectrometry. In another aspect, provided herein are methods for quantitating chromogranin A by mass spectrometry. In another aspect, provided herein are methods for prognosis of or measuring the size of neuroendocrine tumors by mass spectrometry.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: January 30, 2024
    Assignee: Quest Diagnostics Investments LLC
    Inventors: Darren Weber, Michael P. Caufield, Michael McPhaul, Scott Goldman, Nigel Clarke
  • Publication number: 20240026467
    Abstract: Disclosed are methods of identifying a methicillin-resistant Staphylococcus aureus (MRSA) in a sample wherein the methods involve detecting a S. aureus-specific nucleic acid sequence, mecA and mecC, in the sample. Kits for determining the presence of MRSA in a sample are also provided.
    Type: Application
    Filed: June 12, 2023
    Publication date: January 25, 2024
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Lakshmi NAIR, Heather VINCENT, Huong MAI, Michelle TABB, Maurice EXNER
  • Publication number: 20240020529
    Abstract: Present invention is directed to an artificial intelligence-based method and a system, that uses both experimental results data and molecular simulation to predict properties of amorphous solid dispersions such as glass transition temperature, dissolution profile, and/or physical stability. The method and system of the present invention enable rational design of amorphous solid dispersions for poorly water-soluble drugs and significantly reduce the time and resource required for amorphous solid dispersions formulation development.
    Type: Application
    Filed: October 27, 2021
    Publication date: January 18, 2024
    Applicant: ISP INVESTMENTS LLC
    Inventors: Yunxia BI, Thomas DURIG, Solomon Howard JACOBSON
  • Publication number: 20240016709
    Abstract: The present invention provides biodegradable microcapsules, that can encapsulate and retain cargoes such as, lipophilic or hydrophobic core materials comprising fragrances, butters, essential or other oils; or oil solubilized ingredients process of making said biodegradable microcapsules and their applications in various industries. Present invention further provides biodegradable shell materials that show evidence of biodegradation or non-persistence in aquatic based and/or soil or compost based environments.
    Type: Application
    Filed: July 15, 2021
    Publication date: January 18, 2024
    Applicant: ISP INVESTMENTS LLC
    Inventors: Madja AKRACH, Alastair VEITCH, Abdul Wahab HUSSAIN, Alan FERNYHOUGH, Karen MICTHINSON, Claudia VENTURA, Piero de LEONARDIS
  • Publication number: 20240019433
    Abstract: Provided are methods for diagnosing a disease in a subject with a previous streptococcal infection by determining the presence or absence of one or more autoantibodies in a biological sample from the subject, wherein the one or more autoantibodies recognize an antigen from a protein selected from the group consisting of ELAVL2, ELAVL3, ELAVL4, Nova-1, Nova-2, Cdr1, Cdr2; and Cdr3. The presence of such autoantibodies is indicative of a positive diagnosis for a post-streptococcal disease such as PANDAS, post-GABHS glomerulonephritis, rheumatic fever, autism and Syndenham's chorea.
    Type: Application
    Filed: September 25, 2023
    Publication date: January 18, 2024
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Stanley J. NAIDES, Joanna Popov
  • Publication number: 20240016686
    Abstract: A medical cart is provided for use in patient care, the medical cart comprising: a front; a back; sides; four legs which have a distal end, a proximal end and a bore at least partially therebetween terminating in an aperture at the proximal end; an accessory pole releasably retained in the bore; a bracket attached to each leg proximate to the distal end; a caster rotatably attached to each bracket with a caster mount; a lower shelf in engagement with the sides; an upper shelf retained by the sides and an asymmetric handle which defines a gap.
    Type: Application
    Filed: July 13, 2022
    Publication date: January 18, 2024
    Applicant: Dominion Investments LLC
    Inventors: Steven Jay HANSEN, Richard E. OLSEN
  • Publication number: 20240009111
    Abstract: The invention relates to a process for obtaining aqueous extracts of tea leaves (Camellia sinensis), in particular of leaves of fresh tea, pu'er tea, matcha tea or green tea. The invention also relates to tea extracts enriched with small RNAs, sugars, phenolic compounds, organic acids, theine and theanine, as well as to cosmetic compositions comprising such extracts and their cosmetic uses for the care of the skin, the scalp, and the appendages and more particularly for protecting the skin from external aggressions and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin and improving skin hydration.
    Type: Application
    Filed: November 23, 2021
    Publication date: January 11, 2024
    Applicant: ISP INVESTMENTS LLC
    Inventors: Elodie OGER, Laura MOURET
  • Patent number: 11859029
    Abstract: The invention provides a method for preparation of homopolymers and non-homopolymers comprising polymerizing in an aqueous medium a monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety, and optionally at least one hydrophilic or hydrophobic comonomer, in the presence of at least one chain transfer agent and at least one non-radiation initiator. Exemplary diblock polymers prepared by the method have the structure: where subscripts x, y, and z and variables R, R8, R9 and R10 are described herein.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: January 2, 2024
    Assignee: ISP INVESTMENTS LLC
    Inventors: Oliver Johnathan Deane, Osama M. Musa, Steven Peter Armes, Alan Fernyhough, Rebecca Roisin Gibson
  • Patent number: 11860141
    Abstract: Provided are methods for detecting or determining the amount of guanidinoacetate (GAA), creatine, and creatinine by mass spectrometry.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: January 2, 2024
    Assignee: Quest Diagnostics Investments LLC
    Inventor: Thomas C. Lynn
  • Publication number: 20230417700
    Abstract: The present solution describes an automated system for analyzing analytical gels or blots, such as electrophoresis gels. The system can automatically detect the lanes within the gel and convert the lane into a feature vector that can be compared to reference datasets. Based on a comparison of the feature vector to the reference datasets, the system can automatically classify the feature vector (and the test sample in the lane) into a phenotype group.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 28, 2023
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Nilesh Saratkar, Stanley Naides, Michelle A. Cleveland
  • Publication number: 20230416835
    Abstract: The present disclosure relates to methods for the diagnosis and evaluation of neoplastic disorders, particularly non-small cell lung cancer. Assays are described in which patient test samples are analyzed for the presence of one or more specific EML4-ALK fusion genes associated with neoplastic disorders.
    Type: Application
    Filed: May 1, 2023
    Publication date: December 28, 2023
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Heather R. Sanders, Maher Albitar, Aurelia Meloni-Ehrig
  • Patent number: 11851720
    Abstract: Provided herein are methods for identifying the presence or absence of a target nucleic acid from a microorganism using direct amplification without a step of extraction of the nucleic acids, but retaining substantially the same specificity and sensitivity of methods assaying extracted nucleic acids.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: December 26, 2023
    Assignee: Quest Diagnostics Investments LLC
    Inventors: Maurice Exner, Luca Jacky, Yin-Peng Chen, Huong Mai, Michelle M. Tabb, Michael Aye
  • Publication number: 20230407289
    Abstract: The invention provides methods for isolating RNA from whole urine and urine fractions for the diagnosis of prostate cancer and/or benign prostate hyperplasia. An exemplary method for diagnosing prostate cancer in an individual, said method comprises: (a) determining the amount of RNA encoding one or more diagnostic genes in the soluble urine fraction of a urine sample obtained from said individual; (b) comparing the amount of said RNA to a reference value for said one or more diagnostic genes, wherein said reference value is derived from the amount of RNA encoding said one or more diagnostic genes in one or more individuals that do not have prostate cancer; and (c) diagnosing said individual as having prostate cancer when the amount of said RNA is greater than said reference value.
    Type: Application
    Filed: June 5, 2023
    Publication date: December 21, 2023
    Applicant: Quest Diagnostics Investments LLC
    Inventor: Heather R. SANDERS
  • Patent number: D1012032
    Type: Grant
    Filed: May 6, 2021
    Date of Patent: January 23, 2024
    Assignee: One Iron Investments, LLC
    Inventor: Casey Shirts