Patents Assigned to IS2BE
  • ADOPTIVE CELL THERAPY
    Publication number: 20220362304
    Abstract: The invention provides improved methods for adoptive cell therapies for the treatment of cancer.
    Type: Application
    Filed: March 20, 2020
    Publication date: November 17, 2022
    Applicant: 2seventy bio, Inc.
    Inventor: JAMES BRIAN ROTTMAN
  • CHARGING DEVICE FOR ELECTRICAL MACHINES
    Publication number: 20220363158
    Abstract: Charging device for electrical machines, including a body fixable to a wall and including at least a first connector, accessible from the outside, to electrically connect the device and the user to allow the electric charge of the device, a second connector placed within the body and to electrically connect the first connector and a first external electric grid to define a type of mode two charging, and a mode three connector placed within the body and to electrically connect the first connector and a second external electric grid to define a mode three type of charging.
    Type: Application
    Filed: October 29, 2020
    Publication date: November 17, 2022
    Applicant: FREE2MOVE ESOLUTIONS S.P.A
    Inventor: Carlalberto GUGLIELMINOTTI
  • MOSFET manufacturing method
    Patent number: 11502194
    Abstract: An MOSFET manufacturing method, comprising: etching an oxide layer and a silicon nitride layer on a first conductivity type well region, and forming an opening exposing the first conductivity type well region; etching the first conductivity type well region to form a first trench; depositing a medium oxide layer and performing back etching; etching the first conductivity type well region to form a second trench that is connected to the first trench, and forming a grid on an inner wall of the second trench, forming a second conductivity type well region in the first conductivity type well region at the bottom of the second trench, and forming a source in the second conductivity type well region; and removing the oxide layer and the silicon nitride layer, and forming a drain at the first conductivity type well region outside of the trench.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: November 15, 2022
    Assignee: CSMC TECHNOLOGIES FAB2 CO., LTD.
    Inventor: Tse-huang Lo
  • Motion detection device
    Patent number: 11500097
    Abstract: A method includes emitting, by a single sensor of a device, a signal into a region; receiving, by the single sensor, a reflected signal; and detecting motion in a detection cone comprising a central axis based on the reflected signal, wherein detecting motion comprises detecting a first type of motion from a first position to a second position, and detecting a second type of motion from the second position to the first position.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: November 15, 2022
    Assignees: STMicroelectronics SA, STMicroelectronics (Grenoble 2) SAS
    Inventors: Giovanni Scozzola, Olivier Pothier
  • Donor repair templates multiplex genome editing
    Patent number: 11499149
    Abstract: The present disclosure provides improved multiplex genome editing compositions and methods. The disclosure further provides genome edited cells for the prevention, treatment, or amelioration of at least one symptom of a hemoglobinopathy, a cancer, an infectious disease, an autoimmune disease, an inflammatory disease, or an immunodeficiency.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: November 15, 2022
    Assignee: 2seventy bio, Inc.
    Inventors: Baeckseung Lee, Alexander Astrakhan
  • Method for determining the distance separating an object and an optical detection system, and corresponding system
    Patent number: 11500095
    Abstract: A method, for determining the real distance separating an object and an optical detection system, includes, from several so-called reported distances respectively less than or equal to individual reference distances dependent respectively on modulation frequencies: in a first step, determining an initial deviation coefficient between the reported distances and incrementing the smallest of the reported distances with the corresponding individual reference distance; then in a second step, determining a current deviation coefficient between the current distances obtained in the preceding step and incrementing the smallest of the current distances with the corresponding individual reference distance; and in a third step, repeating the second step until all the current distances exceed a common reference distance greater than the individual reference distances.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: November 15, 2022
    Assignee: STMicroelectronics (Grenoble 2) SAS
    Inventor: Pascal Mellot
  • Electronic device comprising optical electronic components and fabricating process
    Patent number: 11502227
    Abstract: An electronic device includes a first electronic component and a second electronic. Each electronic component includes a carrier substrate having a back side and a front side, an electronic chip including an integrated optical element, an overmolded transparent block encapsulating the electronic chip above the carrier substrate, and electrical connections between the electronic chip and electrical contacts of the carrier substrate. An overmolded grid encapsulates and holds the first and second electronic components. The grid is configured so that sides of the first and second electronic components are at least partially exposed.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: November 15, 2022
    Assignee: STMicroelectronics (Grenoble 2) SAS
    Inventors: Romain Coffy, Remi Brechignac, Jean-Michel Riviere
  • Method for measuring quality of therapeutic cell through real-time glutathione measurement
    Patent number: 11499978
    Abstract: The present invention provides a method of measuring the quality of therapeutic cells through real-time glutathione monitoring.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: November 15, 2022
    Assignee: CELL2IN, INC.
    Inventors: Heun Soo Kang, Hye Mi Kim, Ji Eun Song, Gwang Mo Yang, Ji Woong Shin, Hye Won Kang, Yong Hwan Kim, Myung Jin Kim
  • METHOD AND DEVICE FOR THE ENHANCEMENT OF TOPICAL TREATMENTS FOR ORAL MUCOSITIS AND OTHER ORAL CONDITIONS
    Publication number: 20220354629
    Abstract: A method of enhancing absorption of a therapeutic agent sublingually in a person configured to treat chronic graft-versus-host disease (cGVHD) or aphthous stomatitis. The method includes administering a therapeutically effective amount of the therapeutic agent sublingually in a person and then inserting for a predetermined treatment period a device in an oral cavity of the person, wherein the device comprising an oral retention portion that is configured to be retained in the oral cavity from the predetermined treatment period and further configured to enhance absorption of the therapeutic agent sublingually.
    Type: Application
    Filed: July 20, 2022
    Publication date: November 10, 2022
    Applicant: E2BIO LIFE SCIENCES, LLC
    Inventor: Eli D. Ehrenpreis
  • OPTICAL PACKAGE
    Publication number: 20220357536
    Abstract: An optical package includes a substrate made of a first material having an upper surface and a lower surface. The substrate further includes at least one cavity opening onto an upper surface of the substrate. Electrical connection vias extend through the substrate. An electronic integrated circuit chip is mounted on the upper surface of the substrate in a position so as to cover the at least one cavity. The electronic integrated circuit chip includes an integrated optical sensor. Each cavity is filled with a second material having a thermal conductivity greater than the thermal conductivity of the first material. The electrical connection vias are arranged on either side of each cavity and between two cavities.
    Type: Application
    Filed: May 3, 2022
    Publication date: November 10, 2022
    Applicants: STMicroelectronics (Alps) SAS, STMicroelectronics (Grenoble 2) SAS
    Inventors: Deborah COGONI, Raphael GOUBOT, Younes BOUTALEB
  • ELECTRONIC CIRCUIT COMPRISING A RF SWITCHES HAVING REDUCED PARASITIC CAPACITANCES
    Publication number: 20220359435
    Abstract: The present disclosure relates to an electronic circuit comprising a semiconductor substrate, radiofrequency switches corresponding to MOS transistors comprising doped semiconductor regions in the substrate, at least two metallization levels covering the substrate, each metallization level comprising a stack of insulating layers, conductive pillars topped by metallic tracks, at least two connection elements each connecting one of the doped semiconductor regions and formed by conductive pillars and conductive tracks of each metallization level. The electronic circuit further comprises, between the two connection elements, a trench crossing completely the stack of insulating layers of one metallization level and further crossing partially the stack of insulating layers of the metallization level the closest to the substrate, and a heat dissipation device adapted for dissipating heat out of the trench.
    Type: Application
    Filed: April 29, 2022
    Publication date: November 10, 2022
    Applicants: STMicroelectronics (Crolles 2) SAS, STMicroelectronics International N.V.
    Inventors: Stephane MONFRAY, Siddhartha DHAR, Alain FLEURY
  • Lateral flow assay for detecting multiple proteins of a pathogen
    Patent number: 11493509
    Abstract: A lateral flow assay device includes a test strip that is configured to receive a sample fluid and detect a presence of antibodies to one or more of a plurality of proteins of the target pathogen. The lateral flow assay device includes a conjugate pad and a membrane. The conjugate pad contains a plurality of the proteins of the target pathogen, each conjugated with a label. If the sample fluid contains antibodies that are specific to the target pathogen through any of the target pathogen's proteins, a binding takes place between those antibodies and the corresponding tagged protein. The membrane may include a plurality of test lines. Each test line may contain the immobilized binding reagent to one antibody class, resulting in the concentration of all the molecules of that antibody class on the test line.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: November 8, 2022
    Assignee: 2Pi-Sigma Corp.
    Inventor: Mehdi Hatamian
  • Integrated circuit and method of manufacturing the same
    Patent number: 11495609
    Abstract: An integrated circuit includes a high-voltage MOS (HV) transistor and a capacitor supported by a semiconductor substrate. A gate stack of the HV transistor includes a first insulating layer over the semiconductor layer and a gate electrode formed from a first polysilicon. The capacitor includes a first electrode made of the first polysilicon and a second electrode made of a second polysilicon and at least partly resting over the first electrode. A first polysilicon layer deposited over the semiconductor substrate is patterned to form the first polysilicon of the gate electrode and first electrode, respectively. A second polysilicon layer deposited over the semiconductor substrate is patterned to form the second polysilicon of the second electrode. Silicon oxide spacers laterally border the second electrode and the gate stack of the HV transistor. Silicon nitride spacers border the silicon oxide spacers.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: November 8, 2022
    Assignee: STMicroelectronics (Crolles 2) SAS
    Inventors: Fausto Piazza, Sebastien Lagrasta, Raul Andres Bianchi, Simon Jeannot
  • Advanced seismic controller system
    Patent number: 11493655
    Abstract: A method includes receiving over a network from one or more seismic sensors a data set characterizing a seismic event generating a seismic wave. Based on the data set, a time of arrival and intensity of the seismic wave at a predetermined location is calculated. The predetermined location has one or more mitigation devices. Whether the intensity of the seismic wave exceeds a predetermined seismic intensity threshold is determined. If the intensity of the seismic wave exceeds the predetermined seismic intensity threshold, the one or more mitigation devices are activated.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: November 8, 2022
    Assignee: RH2 Engineering, Inc.
    Inventors: James Swanson, Lee Tumbleson, Ryan Mills, Isaac Oquist
  • Drift compensation
    Patent number: 11496170
    Abstract: The present disclosure relates to a method for controlling a device comprising an oscillation circuit, configured to provide a clock signal to a radio frequency circuit, and an antenna, in which the enabling of the passage of the signal from the circuit to the antenna is delayed with respect to an instant from which a power amplifier of the circuit is enabled.
    Type: Grant
    Filed: February 20, 2021
    Date of Patent: November 8, 2022
    Assignees: STMicroelectronics (Alps) SAS, STMicroelectronics S.r.l., STMicroelectronics (Grenoble 2) SAS
    Inventors: Benoit Marchand, Hamilton Emmanuel Querino De Carvalho, Daniele Mangano, Santo Leotta
  • Airfoils and Machines Incorporating Airfoils
    Publication number: 20220348270
    Abstract: Various embodiments of an airfoil and machines with airfoils are disclosed. The airfoils include a thicker leading airfoil portion and a thinner trailing airfoil portion. In one embodiment, the leading airfoil portion is formed by bending a body of the airfoil back toward itself. In another embodiment, the leading airfoil portion has a solid geometry and includes two elliptic surfaces. To prevent detachment of airflow, the leading airfoil portion includes at least two arc portions or surfaces that act to direct the airflow down to the trailing airfoil portion in a manner that stabilizes vortexes that may form in the region of changing thickness.
    Type: Application
    Filed: June 16, 2022
    Publication date: November 3, 2022
    Applicant: ESS 2 Tech, LLC
    Inventors: Michael Suk, David A. Shoffler
  • PATIENT-SPECIFIC INSTRUMENTS FOR PERFORMING BONE CUTS
    Publication number: 20220346806
    Abstract: An apparatus and a method are provided for a patient-specific instrument guide for arthroplasty or other operations on bone tissue, capable of limiting bone cuts, achieving optimal implant positioning, and providing improved stability of implants. The patient-specific instrument guide comprises a body that includes a bone contact surface configured to contact a bone surface of a patient. The body is configured to be 3D printed according to medical imaging of a patient's anatomy, such that the bone contact surface optimally contacts the surface of the patient's bone. The body includes one or more guide slots that each slidably receives a cutting guide. The cutting guides are configured to receive a saw blade during bone cutting. The cutting guides may be oriented to guide cutting a talus or a tibia during a total ankle arthroplasty surgery.
    Type: Application
    Filed: May 28, 2020
    Publication date: November 3, 2022
    Applicant: ln2Bones SAS
    Inventors: Thibaut Jean Perry Leemrijse, Pit Putzeys, Laurent Francois Rene Paul, Per-Henrik Agren, Jean-Luc Pierre Marie Besse
  • ADJUSTABLE LANCET AND TEST CARTRIDGE FOR AUTOMATED MEDICAL SAMPLE COLLECTION AND TESTING
    Publication number: 20220346680
    Abstract: A test cartridge includes an adjustable lancet. The adjustable lancet is controlled by a controller. The adjustable lancet automatically detects a subject's finger, adjusts the lancet's height, pricks the finger to draw blood, moves a tube to collect the blood, moves the tube away from the finger, and empties the blood from the tube into a vial or receptacle. The adjustable lancet may include safety features to prevent the lancet to trigger when the subject's fingernail is facing the lancet, to control the amount that the lancet pierces the subject's finger, and/or to prevent the reuse of a test cartridge for multiple persons or multiple times by the same person. The adjustable lancet may include a massager wheel and/or a pressure bar to rub the subject's finger after the finger is pierced to facilitate drawing of the blood from the finger.
    Type: Application
    Filed: July 13, 2022
    Publication date: November 3, 2022
    Applicant: 2Pi-Sigma Corp.
    Inventor: Mehdi Hatamian
  • Bottle cap with fan
    Patent number: D969538
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: November 15, 2022
    Assignee: O2COOL, LLC
    Inventors: Tom Zeng, Ryan Ruan
  • Misting fan
    Patent number: D969990
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: November 15, 2022
    Assignee: O2COOL, LLC
    Inventors: Tom Zeng, Jeff Bull