Patents Assigned to Isconova AB
  • Publication number: 20130129770
    Abstract: The present invention relates to a composition comprising at least one ISCOM complex and at least one ectodomain from at least one hemagglutinin (HA) domain and at least one ectodomain from at least one neuraminidase (NA) domain from one or more influenza virus, wherein the extodomains represent ectodomains isolated from the influenza virus. The invention also regards a kit. The composition may be used as an immune stimulating medicine, immune modulating pharmaceutical or a vaccine e.g. against influenza for vertebrates, e.g. birds and mammals.
    Type: Application
    Filed: July 25, 2011
    Publication date: May 23, 2013
    Applicants: ERASMUS UNIVERSITY ROTTERDAM MEDICAL CENTER, ISCONOVA AB
    Inventors: A.D.M.E. Osterhaus, Bror Morein, Karin Bengtsson Lövgren
  • Patent number: 8187585
    Abstract: The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the preparation of a vaccine against a micro organism that comprises at least one fibronectin binding domain. It also relates to a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fibronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an iscom matrix complex and/or an iscom complex and or a liposome.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: May 29, 2012
    Assignee: Isconova AB
    Inventors: Bror Morein, Karin Lövgren Bengtsson, Jill Ekstrom, Katarina Ranlund, Birgitta Fromgren, Carlos Concha Bascunan
  • Publication number: 20120107353
    Abstract: The invention relates to a composition comprising at least one ISCOM complex and at least one internal antigen which is not a surface antigen and not in the form of a part of a whole micro-organism. The internal antigen may be a nucleoprotein or presented as a member of the group of components obtained after disintegrating a micro-organism. The ISCOM complex may be an ISCOM or ISCOM matrix complex. The composition may also comprise non internal antigens. The invention also elates to the composition for use as an immune stimulating medicine or vaccine, especially for use in eliciting T cell respond including CTL respond. The invention also relate to a composition comprising at least one ISCOM complex for use as an immune stimulating or immune modulating medicine or vaccine for the stimulation of dendritic ceils in elderly.
    Type: Application
    Filed: July 9, 2010
    Publication date: May 3, 2012
    Applicant: ISCONOVA AB
    Inventors: Bror Morein, Karin Lövgren Bengtsson
  • Publication number: 20110303563
    Abstract: The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the preparation of a vaccine against a micro organism that comprises at least one fibronectin binding domain. It also relates to a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fibronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an iscom matrix complex and/or an iscom complex and or a liposome.
    Type: Application
    Filed: July 20, 2011
    Publication date: December 15, 2011
    Applicant: Isconova AB
    Inventors: Bror Morein, Karin Lövgren-Bengtsson, Katarina Ranlund, Birgitta Fromgren, Jill Ekstrom, Carlos Concha Bascunan
  • Patent number: 8007806
    Abstract: The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; and at least one Iscom matrix complex and/or liposome and/or at least one lipid and at least one saponin, whereby the at least one lipid and the at least one saponin may be in complex, solution or suspension. Further, it regards use thereof for the production of a vaccine against a micro organism that comprises at least one one fibronectin binding domain. It also regards a kit of parts comprising at least two compartments, wherein one compartment comprises at least one truncated fibronectin binding protein and/or a fibronectin binding peptide, that comprises at least one fibronectin binding domain, and another compartment comprises an instruction for use and/or an Iscom matrix complex and/or an iscom complex and or a liposome.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: August 30, 2011
    Assignee: Isconova AB
    Inventors: Bror Morein, Karin Lövgren-Bengtsson, Katarina Ranlund, Birgitta Fromgren, Jill Ekstrom, Carlos Concha Baschunan
  • Publication number: 20110081378
    Abstract: Iscom particles can be used as an adjuvant for preparing of an antigenic composition which comprises live micro-organisms and/or killed micro-organisms and/or antigenic molecules. A composition may comprise at least one iscom particle and one or more live micro-organisms and/or killed micro-organisms and/or antigenic molecules. A kit can comprise at least one compartment containing at least one living organism and at least one compartment containing at least one iscom particle.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 7, 2011
    Applicant: Isconova AB
    Inventors: Bror Morein, Karin Lovgren Bengtsson
  • Patent number: 7838019
    Abstract: Iscom particles can be used as an adjuvant for preparing of an antigenic composition which comprises live micro-organisms and/or killed micro-organisms and/or antigenic molecules. A composition may comprise at least one iscom particle and one or more live micro-organisms and/or killed micro-organisms and/or antigenic molecules. A kit can comprise at least one compartment containing at least one living organism and at least one compartment containing at least one iscom particle.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: November 23, 2010
    Assignee: Isconova AB
    Inventors: Bror Morein, Karin Lovgren Bengtsson