Abstract: Saponin preparations based on defined compositions of purified saponin fractions derived from the bark of Quillaja saponaria Molina are disclosed. The saponin preparations are useful in immunostimulating complex (iscom) matrices. The saponin preparations, and iscom matrices prepared using them, have particular activity as adjuvants.
Type:
Grant
Filed:
February 22, 1999
Date of Patent:
March 5, 2002
Assignee:
Iscotec A.B.
Inventors:
John Cooper Cox, Alan Robert Coulter, Bror Morein, Karin Lovgren-Bengtsson, Bo Sundquist