Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxide dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.
Type:
Application
Filed:
January 10, 2011
Publication date:
February 2, 2012
Applicant:
Isis Corporation
Inventors:
C. Frank Bennett, Kenneth W. Dobie, Susan M. Freier