Patents Assigned to ISIS INNOVATION, Inc.
  • Therapeutic antibodies
    Patent number: 7465790
    Abstract: A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: December 16, 2008
    Assignee: ISIS INNOVATION, Inc.
    Inventors: Herman Waldmann, Mark Raymond Frewin, Lisa Kim Gilliland, Luis Richardo Simoes da Silva Graca