Abstract: An isolator (10) formed to facilitate the entry and exit of products into and out of the isolator, the wall (12) of which includes an upper part (16) and a lower part (18) capable of being disconnected completely along one section of the isolator. The upper part (16) includes a flexible wall (24) forming a skirt, the lower edge of which emcompasses the upper edge of the lower part (18). A sealed connection of the two parts is obtained by inflating an inflatable seal (36) mounted in a recess (34) formed in a rigid portion of the lower part (18). The seal (36) then comes into sealing contact with an unstretchable belt (26) affixed to the lower end of the flexible wall (24).