Patents Assigned to Isomed, Inc.
  • Patent number: 5858398
    Abstract: A pharmaceutical composition comprises microparticles in micelle. The microparticles contain at least one pharmaceutically-active agent, at least one water soluble or miscible phospholipid, at least one lipid soluble or miscible phospholipid, at least one non-ionic surfactant having an HLB value of about 15 or greater, at least one non-ionic surfactant having an HLB value of about or less, and at least one water soluble or miscible sterol compound. The microparticles are suspended in at least one fatty acid having a chain length of C.sub.14 or less. The composition may optionally contain at least one fatty acid having a chain length of C.sub.16 or greater in a concentration of about 5 w/v % or less. The composition is prepared by admixing the pharmaceutically-active agent, phospholipids, surfactants, and sterol, micronizing the admixture to form microparticles, and suspending the microparticles in at least one fatty acid of chain length of C.sub.14 or less to form microparticles in micelle.
    Type: Grant
    Filed: May 2, 1996
    Date of Patent: January 12, 1999
    Assignee: Isomed Inc.
    Inventor: Young W. Cho
  • Patent number: 4862143
    Abstract: A counterfeit detecting method and apparatus are provided for detecting the authenticity of an article having a label containing an isotope of a chemical element. The apparatus comprises a housing, a source of gamma radiation positioned in the housing, and a gamma radiation detector positioned in the housing for detecting the radiation from the source. The gamma radiation source is selected to emit radiation which can stimulate a selected nuclear transition in the label material. A calculating device, such as a microprocessor is coupled to a detector for calculating the ratio of the number of gamma rays counted by the detector during a predetermined period of time when the article is not in position near the receiving member (N.sub.O) to the number of the gamma rays counted by the detector during a period of time equal to the predetermined period when the article is positioned near the receiving means (N.sub.
    Type: Grant
    Filed: February 1, 1988
    Date of Patent: August 29, 1989
    Assignee: Isomed, Inc.
    Inventors: Jay L. Hirshfield, Israel Nowik
  • Patent number: 4755671
    Abstract: A method and apparatus for separating plural isotopes of a chemical substance is disclosed. The apparatus comprises a first magnetic field generating device for generating a uniform axial first magnetic field and a second magnetic field generating device such as a wiggler for generating a non-uniform, twisted, second magnetic field. An ion source provides a stream of ions of isotopes to be separated, the stream passing through the first and second magnetic fields. Ions of different charge-to-mass ratio will follow different trajectories or paths through the magnetic fields. A collector is positioned with respect to the second magnetic field generating device such that only the ions of isotopes to be collected strike the collector means and are collected thereon.
    Type: Grant
    Filed: January 31, 1986
    Date of Patent: July 5, 1988
    Assignee: Isomed, Inc.
    Inventors: Lazar Friedland, Michael Geva, Jay Hirshfield
  • Patent number: 4742340
    Abstract: A counterfeit detecting method and apparatus are provided for detecting the authenticity of an article having a label containing an isotope of a chemical element enriched to a predetermined amount. The apparatus comprises a housing, a source of gamma radiation positioned in the housing, and a gamma radiation detector positioned in the housing for detecting the radiation from the source. The gamma radiation source is selected to emit radiation which can stimulate a selected nuclear transition in the label material. A calculating device, such as a microprocessor, is coupled to a detector for calculating the ratio of the number of gamma rays counted by the detector during a predetermined period of time when the article is not in position near the receiving member (N.sub.O) to the number of the gamma rays counted by the detector during a period of time equal to the predetermined period when the article is positioned near the receiving member (N.sub.
    Type: Grant
    Filed: December 4, 1986
    Date of Patent: May 3, 1988
    Assignee: Isomed, Inc.
    Inventors: Israel Nowik, Jay L. Hirshfield