Abstract: A co-processed excipient composition comprising (i) vinyl lactam derived polymer; (ii) silica; and (iii) at least one lubricant is provided in the present disclosure. The co-processed excipient has a Brookfield flow factor of 5 to 9. Also provided a process for preparing the same. The co-processed excipient is used further in continuous or direct compression batch manufacturing with superior flow properties and self-lubrication.

Abstract: The invention provides radiation sensitive films, radiation dosage indicators comprising these films, processes for preparing these films, and methods of use of these films in several industrial and domestic applications that require exposure to radiation for certain benefits. The radiation sensitive films comprise a radiation sensitive composition typically in the form of a film which is overlaid by an uncolored and optically transparent layer for increasing the radiation sensitivity of the films.

Abstract: The invention relates to processes for preparing plant extracts comprising an autofermentation step and optionally extraction steps allowing enrichment of the extracts with small molecular weight RNA. The invention also relates to compositions comprising such extracts and their cosmetic uses to combat the signs of skin aging. loss of firmness or tone. improve barrier function and hydration. lighten the skin or improve the skin's innate immune defenses and well-being in vivo.

Abstract: Disclosed is a water-soluble biodegradable dispersant composition having a low to medium molecular weight carboxylated polysaccharide functionalized with at least one mono-valent (M+) cation and at least one di-valent (M++) cation and an optional adjunct material. More particularly, a laundry or detergent composition provides soil resistant textiles by means of treatment with an anti-soil redeposition agent carboxymethyl cellulose (CMC) comprising sodium-calcium carboxymethyl cellulose, sodium-magnesium carboxymethyl cellulose, sodium-zinc carboxymethyl cellulose. sodium-calcium-zinc carboxymethyl cellulose, sodium-calcium-magnesium-carboxymethyl cellulose or sodium-magnesium-zinc-carboxymethyl cellulose.

Abstract: The present invention relates to a method for obtaining a bioactive serum fraction derived from fresh rose flowers (Rosa spp.). The present invention also provides bioactive serum fractions and bioactive extracts derived from fresh rose flowers (Rosa spp.) and compositions comprising the same. The present invention further relates to a method of cosmetic treatment for improving skin appearance associated with antioxidant and antiaging properties of the bioactive serum fraction and the bioactive extract derived from fresh rose flowers (Rosa spp.).

Abstract: In accordance with the present invention there is provided an oil-in-water emulsion sunscreen composition comprising (a) a UV active, (b) a first emulsifier having an HLB value less than 5 and (c) optionally a second emulsifier having an HLB value greater than 5 present in an amount of less than 0.2% w/w of the composition. The oil-in-water sunscreen composition is characterized by the absence of an emulsifiable polymer and is capable of providing little to no whitening when applied to wet skin.

Abstract: The present application provides high solids film coating compositions comprising a water-soluble cellulose ether, hydroxy propyl cellulose (HPC), a poly (N-vinyl pyrrolidone-co-vinyl acetate) copolymer, a film-forming agent based on D-glucose, plasticizer, medium chain triglycerides (MCT) and an anti-tack agent. The invention further provides a process for preparing the above described film coating compositions and method of coating solid substrate with such coating compositions.

Abstract: Described herein is a synergistic preservative composition used for providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds selected from the group consisting of propanediol, capryl hydroxamic acid, and isopropyl methyl phenol; and (iii) about 0.1 wt. % to 99.0 wt. % of phenoxyethanol, a preservative compound, and wherein, the composition provides synergy having Synergy Index (SI) value of the total composition from about 0.05 to about 1.0. Also described is a process for preparing said synergistic preservative composition and method of using the same.

Abstract: The present invention relates to compositions and methods for improving the appearance of the skin. Compositions comprises at least water, glycerin, sodium PCA, erythritol, Carrageenan (Chondrus Crispus extract), xanthan Gum; hydrolyzed collagen, hexapeptide-9 and a physiologically acceptable medium. Methods comprise applying the compositions to the skin to improve the appearance of aging skin, increasing skin moisturization, refining skin pores and decreasing aging skin pigmentation defects.

Abstract: The present invention relates to compositions and methods for improving the appearance of the skin. Compositions comprises at least water, glycerin, sodium PCA, erythritol, Carrageenan (Chondrus Crispus extract), xanthan Gum; hydrolyzed collagen, hexapeptide-9 and a physiologically acceptable medium. Methods comprise applying the compositions to the skin to improve the appearance of aging skin, increasing skin moisturization, refining skin pores and decreasing aging skin pigmentation defects.

Abstract: This application provides reactive, flexible, water-resistant hydroxyethylpyrrolidone methacrylate/glycidyl methacrylate copolymers having the structure: wherein a and b are integers, the sum of which less than 100, covalently linked to active agents that are useful in a wide variety of compositions. The present application also discloses hydroxyethylpyrrolidonemethacrylate/glycidyl methacrylate copolymer convently linked to one or more surface active moiety having a structure: wherein a, b, and c are integers, the sum of which equals 100, and M is a surface-active moiety.

Abstract: A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.

Abstract: Present invention is directed to an artificial intelligence-based method and a system, that uses both experimental results data and molecular simulation to predict properties of amorphous solid dispersions such as glass transition temperature, dissolution profile, and/or physical stability. The method and system of the present invention enable rational design of amorphous solid dispersions for poorly water-soluble drugs and significantly reduce the time and resource required for amorphous solid dispersions formulation development.

Abstract: The present invention provides biodegradable microcapsules, that can encapsulate and retain cargoes such as, lipophilic or hydrophobic core materials comprising fragrances, butters, essential or other oils; or oil solubilized ingredients process of making said biodegradable microcapsules and their applications in various industries. Present invention further provides biodegradable shell materials that show evidence of biodegradation or non-persistence in aquatic based and/or soil or compost based environments.

Abstract: The invention relates to a process for obtaining aqueous extracts of tea leaves (Camellia sinensis), in particular of leaves of fresh tea, pu'er tea, matcha tea or green tea. The invention also relates to tea extracts enriched with small RNAs, sugars, phenolic compounds, organic acids, theine and theanine, as well as to cosmetic compositions comprising such extracts and their cosmetic uses for the care of the skin, the scalp, and the appendages and more particularly for protecting the skin from external aggressions and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin and improving skin hydration.

Abstract: The invention provides a method for preparation of homopolymers and non-homopolymers comprising polymerizing in an aqueous medium a monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety, and optionally at least one hydrophilic or hydrophobic comonomer, in the presence of at least one chain transfer agent and at least one non-radiation initiator. Exemplary diblock polymers prepared by the method have the structure: where subscripts x, y, and z and variables R, R8, R9 and R10 are described herein.

Abstract: The invention relates to a process for obtaining an aqueous extract of lavender enriched with small RNAs of a maximum length of 150 nucleotides, with sugars, with phenolic compounds, with organic acids and devoid of DNA, obtained by the following process: the lavender aerial parts are brought into contact with water; phytic acid is added at a pH of between 10 and 11; the pH of the mixture obtained is then adjusted to a value of between 6 and 8, the mixture obtained is purified. The invention also relates to cosmetic compositions comprising such an extract and their cosmetic uses for protecting the skin from external aggression and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin, improving hydration, reinforcing the barrier function, soothing the skin or improving the biological mechanisms associated with skin repair during the night.

Abstract: The present invention relates to composition comprising a bioactive fractions (ingredients) derived from fruit juice of an Apple (Pyrus malus) produced by processing the fresh fruit of apple under conditions effective to yield a bioactive fraction that is substantially free of protein and patulin. The present invention also relates to compositions having antioxidant and free radical scavenging properties and suitable for topical applications, oral applications and functional drink applications.

Abstract: The present invention provides bioactive compositions comprising Ficus serum fraction derived from Ficus cell juice of fresh Ficus leaves and a process of preparing the Ficus serum fraction. The compositions have biological activity capable of reducing skin hyperpigmentation.

Abstract: Disclosed herein are methods of improving skin appearance associated with skin aging. The method comprises the step of applying an anti-aging bioactive composition to a skin surface having at least one sign of aging. The anti-aging bioactive composition is applied for a period of time sufficient to improve the appearance of the at least one sign of aging. In one embodiment, the anti-aging bioactive composition comprises an effective amount of a Nelumbo nucifera (Sacred Lotus) serum fraction. In another embodiment, the anti-aging bioactive composition comprises an effective amount of a Chamomilla recutita (German Chamomile) Flower serum fraction. In other embodiments, the anti-aging bioactive composition can further include a dermatologically acceptable carrier.