Patents Assigned to Istituo Nazionale per lo Studio e la Cura dei Tumori
  • Camptothecin derivatives having antitumor activity
    Patent number: 7105492
    Abstract: Camptothecin derivatives of camptothecin of formula (I) exhibit antitumor activity and show a good therapeutic index and are used in the treatment of tumors, viral infections and antiplasmodium falciparum.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: September 12, 2006
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Istituo Nazionale Per Lo Studio E La Cura Dei Tumori
    Inventors: Sabrina Dallavalle, Sergio Penco, Claudio Pisano, Franco Zunino
  • Camptothecin derivatives having antitumor activity
    Publication number: 20040018988
    Abstract: Camptothecin derivatives of camptothecin of formula (I) 1
    Type: Application
    Filed: March 17, 2003
    Publication date: January 29, 2004
    Applicants: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Istituo Nazionale per lo Studio e la Cura dei Tumori
    Inventors: Sabrina Dallavalle, Sergio Penco, Claudio Pisano, Franco Zunino
  • Camptothecin derivatives having antitumor activity
    Patent number: 6242457
    Abstract: Camptothecin derivatives of camptothecin of formula (I) wherein the groups R1, R2 and R3 are as defined in the description are disclosed. The compounds of formula (I) are endowed with antitumor activity and show a good therapeutic index. Processes for the preparation of the compounds of formula (I) and their use in the preparation of medicaments useful in the treatment of tumors, viral infections and antiplasmodium falciparum are also disclosed.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: June 5, 2001
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Istituo Nazionale per lo Studio e la Cura dei Tumori
    Inventors: Sergio Penco, Lucio Merlini, Paolo Carminati, Franco Zunino