Patents Assigned to Istituto Chimico Internazionale Dr. Giuseppe Rende S.r.l.
  • Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same
    Patent number: 5270338
    Abstract: Compounds related to acetazolamide and to its N-methyl derivatives, of the formula: ##STR1## wherein Y is one of the following groups: ##STR2## R.sub.1 being a straight or branched alkylene or arylalkylene, or a phenylene, and the processes for their preparation; the compounds so obtained are inhibitors of carbonic anhydrase like acetazolamide but, in addition, they are well absorbed topically so that they can be used as drugs for treating glaucoma.
    Type: Grant
    Filed: March 29, 1991
    Date of Patent: December 14, 1993
    Assignee: Istituto Chimico Internazionale Dr. Giuseppe Rende S.r.l.
    Inventors: Antonaroli Simonetta, Bianco Armandodariano, Mario Brufani, Lo B. Giuseppe, Giorgio Rende