Patents Assigned to Istituto Oncologico Veneto
  • Water soluble furoxan derivatives having antitumor activity
    Patent number: 8946271
    Abstract: Water soluble compounds having a furoxan structure which are capable of inhibiting metabolic pathways involved in the development of the tumours are provided. The use of such compounds as a medicament in the therapy of the tumours and as an adjuvant in the immunotherapy protocols against neoplasms is also described.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: February 3, 2015
    Assignees: Humanitas Mirasole S.p.A., Istituto Oncologico Veneto IRCCS
    Inventors: Antonella Viola, Enzo Bronte, Marco Crosetti, Loretta Lazzarato, Roberta Fruttero, Alberto Gasco
  • Nitric oxide furoxan derivative compounds endowed with antitumoral activity
    Patent number: 8592464
    Abstract: The present invention relates to nitric oxide furoxan derivative compounds which showed to be active in the treatment of tumors. In addition, they may be used as adjuvants in cancer immunotherapy.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: November 26, 2013
    Assignees: Humanitas Mirasole S.p.A., Istituto Oncologico Veneto IRCCS
    Inventors: Antonella Viola, Enzo Bronte, Marco Crosetti, Loretta Lazzarato, Roberta Fruttero, Alberto Gasco
  • MYELOID-DERIVED SUPPRESSOR CELLS GENERATED IN VITRO
    Publication number: 20120225038
    Abstract: A population of myeloid-derived suppressor cells and the culture procedure to obtain these in vitro starting with bone marrow cells of mice, other animals and human beings, in the presence of specific cytokine combinations used to determine concentrations, is provided.
    Type: Application
    Filed: January 28, 2009
    Publication date: September 6, 2012
    Applicant: Istituto Oncologico Veneto
    Inventors: Vincenzo Bronte, Susanna Mandruzzato