Patents Assigned to Istituto Sieroterapico e Vaccinogeno Toscano "Sclavo" S.p.A.
  • Patent number: 4388295
    Abstract: A method and an implementation are disclosed for measuring the contents of a certain component (e.g. a hormone) in a biological fluid. The basic principle of the method is that a complex is formed starting from the antagonist of the component sought for with the product of conjugation of the latter with a tracer (e.g. a radioisotope), said complex is introduced in the biological fluid to be tested and the quantity of the tracer which has been set free is measured with a measuring or dosing technique which is appropriate for the tracer which has been selected.
    Type: Grant
    Filed: May 30, 1980
    Date of Patent: June 14, 1983
    Assignee: Istituto Sieroterapico e Vaccinogeno Toscano "Sclavo" S.p.A.
    Inventors: Francesco Cocola, Paolo Tarli, Paolo Neri
  • Patent number: 4306020
    Abstract: A novel composition is disclosed for determining the activity of the alkaline phosphatase, which comprises a salt of p-nitrophenylphosphoric acid, a magnesium salt, sodium borate and 2-amino-2-hydroxymethyl-1,3-propanediol. The composition affords advantages over the known composition especially as regards sensitivity.
    Type: Grant
    Filed: September 25, 1980
    Date of Patent: December 15, 1981
    Assignee: Istituto Sieroterapico E Vaccinogeno Toscano "SCLAVO" S.p.A.
    Inventor: Franco Meiattini
  • Patent number: 4220714
    Abstract: A method and a combination of reagents are disclosed for determining the creatine kinase activity by inhibiting the action of creatine kinase, the improvement consisting in that adenosine - 5'- monophosphate is used in combination with an inorganic, preferably an alkali metal, fluoride. By so doing the masking effect of adenylate kinase are efficiently offset.
    Type: Grant
    Filed: April 13, 1978
    Date of Patent: September 2, 1980
    Assignee: Istituto Sieroterapico e Vaccinogeno Toscano Sclavo S.p.A.
    Inventors: Franco Meiattini, Giuliano Giannini, Paolo Tarli
  • Patent number: 4148609
    Abstract: A method for measuring the antistreptolysin concentration in a human blood sample by adding a solution of oxidized 0-streptolysin to the blood sample (diluted), incubating, reacting with a reducing solution, incubating and relating the resulting hemolysis to the antistreptolysin concentration.
    Type: Grant
    Filed: December 2, 1976
    Date of Patent: April 10, 1979
    Assignee: Istituto Sieroterapico e Vaccinogeno Toscano "Sclavo" S.p.A.
    Inventor: Antonio Ricci
  • Patent number: D245583
    Type: Grant
    Filed: May 4, 1976
    Date of Patent: August 30, 1977
    Assignee: Istituto Sieroterapico e Vaccinogeno Toscano "Sclavo" S.p.A.
    Inventor: Enzo Sergio Mannucci
  • Patent number: RE29498
    Abstract: Process for enzymatic determination of glucose with a glucose-oxidase-peroxidase enzyme system involving the use of a reduced acceptor which is oxidized. As reduced acceptor in the enzymatic reaction catalyzed by peroxidase, a ferrocyanide salt is oxidized to ferricyanide; then a further reducing system is introduced, which system is oxidized by the ferricyanide, with the formation of a colored quinone compound, the reaction between ferricyanide and the reducing system taking place spontaneously.
    Type: Grant
    Filed: March 2, 1976
    Date of Patent: December 20, 1977
    Assignee: Istituto Sieroterapico e Vaccinogeno Toscano "SCLAVO", S.p.A.
    Inventor: Franco Meiattini
  • Patent number: RE31372
    Abstract: A method for measuring the antistreptolysin concentration in a human blood sample by adding a solution of oxidized O-streptolysin to the blood sample (diluted), incubating, reacting with a reducing solution, incubating and relating the resulting hemolysis to the antistreptolysin concentration.
    Type: Grant
    Filed: April 8, 1981
    Date of Patent: September 6, 1983
    Assignee: Istituto Sieroterapico e Vaccinogeno Toscano "Sclavo" S.p.A.
    Inventor: Antonio Ricci