Abstract: This invention is concerned with the use of adenosine as an agent for the treatment of human beings. More particularly, this invention is concerned with the administration of adenosine to human patients by continuous intravenous infusion for, inter alia, control of blood pressure, use as a selective vasodilator, decreasing pulmonary vascular resistance, treating acute pulmonary hypertension in conjunction with idiopathic respiratory distress syndrome, in diagnosing pulmonary hypertension in conjunction with cardiac septum defects, in percutaneous transluminal angioplasty (PTCA), in coronary thrombolysis (CTL) and in radionucleide scintography.
Abstract: The described invention relates to the treatment of hyperexcited sensory nerve functions, e.g., neuropathia in human subjects, comprising parenteral administration of an amount of an adenosine receptor agonist to said subjects. It is demonstrated that an adenosine receptor agonist can alleviate or normalize hyperexcited sensory nerve functions such as the perception of touch, temperature, vibration, pain, pressure and disturbances in other sensory functions.
Abstract: The described invention relates to a method of treatment of a pulmonary inflammatory reaction brought about by e.g. bacteraemia, physical trauma or viral infection, with activation of polymorphonuclear white blood cells, said method comprising continuous intravenous infusion of adenosine at a rate effective for such treatment, preferably 2 to 50 .mu.g/ml/min, more preferably 5-20 .mu.g/kg/min in a central vein.
Abstract: A dispenser for medical preparations comprises a rectangular box (1) which releasably accommodates an insert (3) for containing a series of countersunk compartments (4) for receiving the medical preparations, the box having a top cover with slidable shutters (5) adapted to be opened at least partially to permit access to the contents of the respective compartments, a protective lid (7, 7") being removably arranged the top of the insert and covering the compartments and being openable to permit the abovementioned access. The lid (7; 7") can be peeled off or slidably removed from the insert (2) and has a grip portion (10; 10") that can be seized externally of one side of the box permit peeling off or sliding of the lid respectively through an opening or a slot (6; 6") provided in said box side.
Abstract: A dispenser for medical preparations includes a rectangular box having a bottom and a top portion. The top portion has a plurality of apertures, each aperture covered by a lid that is slidable in grooves in the top portion so that the lid is extractable in one direction. An insert having several rows of compartments for medical preparations is adapted to be inserted in the box so that each row is positioned under an aperture for access to the compartments through the corresponding overlying aperture. A cover which closes an opening in a side of the box is removable to allow the insertion and removal of the insert through the opening. A locking rod locks the lids in a position closing the apertures, and unlocks all of the lids at the same time. The cover is also locked in a closing position by the locking rod and is removable only upon actuation of the locking rod for unlocking the lids.