Abstract: The present disclosure relates to combinations of valproic acid or a pharmaceutically acceptable salt thereof, a ?-lactam compound or a pharmaceutically acceptable salt thereof, and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the combinations.
Type:
Grant
Filed:
March 11, 2021
Date of Patent:
October 29, 2024
Assignee:
Iterum Therapeutics International Limited
Abstract: The present disclosure relates to combinations of a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease via administering to subjects in need thereof a ?-lactam compound or a pharmaceutically acceptable salt thereof and probenecid or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
December 13, 2022
Date of Patent:
October 8, 2024
Assignee:
Iterum Therapeutics International Limited
Abstract: The present disclosure relates to bilayer tablets comprising a second layer comprising a ?-lactam compound or a pharmaceutically acceptable salt thereof; and a first layer comprising probenecid or a pharmaceutically acceptable salt thereof. The present disclosure also relates to methods of treating or preventing a disease using the bilayer tablets.
Type:
Grant
Filed:
December 23, 2019
Date of Patent:
October 25, 2022
Assignee:
Iterum Therapeutics International Limited
Inventors:
Michael Dunne, Tom Loughman, Aaron Cameron