Patents Assigned to Ithaca College
  • Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same
    Patent number: 11608308
    Abstract: Aspects of the present disclosure include fatty acid ?-hydroxyester compounds (e.g., fatty acid esters of ?-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid ?-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: March 21, 2023
    Assignees: The J. David Gladstone Institutes, The Regents of The University Of California, Ithaca College
    Inventors: Eric Verdin, Scott Michael Ulrich, John C. Newman
  • Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same
    Patent number: 10889538
    Abstract: Aspects of the present disclosure include fatty acid ?-hydroxyester compounds (e.g., fatty acid esters of ?-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid ?-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: January 12, 2021
    Assignees: The J. David Gladstone Institutes, The Regents of The University Of California, Ithaca College
    Inventors: Eric Verdin, Scott Michael Ulrich, John C. Newman
  • Inhibitors of kidney-type glutaminase, GLS-1
    Patent number: 10889585
    Abstract: The present invention relates generally to glutaminase inhibitors of Formula I, Formula II, or Formula III, as well as pharmaceutical compounds containing them and methods of their use.
    Type: Grant
    Filed: January 6, 2020
    Date of Patent: January 12, 2021
    Assignees: CORNELL UNIVERSITY, ITHACA COLLEGE
    Inventors: Richard Cerione, Kristin Cerione, Clint Stalnecker, Scott Ulrich
  • Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same
    Patent number: 10647658
    Abstract: Aspects of the present disclosure include fatty acid ?-hydroxyester compounds (e.g., fatty acid esters of ?-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid ?-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: May 12, 2020
    Assignees: The J. David Gladstone Institutes, The Regents of The University Of California, Ithaca College
    Inventors: Eric Verdin, Scott Michael Ulrich, John C. Newman
  • Medium chain fatty acid esters of ?-hydroxybutyrate and butanediol and compositions and methods for using same
    Patent number: 10562839
    Abstract: Aspects of the present disclosure include fatty acid ?-hydroxyester compounds (e.g., fatty acid esters of ?-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid ?-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: February 18, 2020
    Assignees: The J. David Gladstone Institutes, The Regents of The University Of California, Ithaca College
    Inventors: Eric Verdin, Scott Michael Ulrich, John C. Newman
  • Inhibitors of kidney-type glutaminase, GLS-1
    Patent number: 10526322
    Abstract: The present invention relates generally to glutaminase inhibitors of Formula I, Formula II, or Formula III, as well as pharmaceutical compounds containing them and methods of their use.
    Type: Grant
    Filed: December 5, 2015
    Date of Patent: January 7, 2020
    Assignees: Cornell University, Ithaca College
    Inventors: Richard Cerione, Kristin Cerione, Clint Stalnecker, Scott Ulrich
  • MEDIUM CHAIN FATTY ACID ESTERS OF BETA-HYDROXYBUTYRATE AND BUTANEDIOL AND COMPOSITIONS AND METHODS FOR USING SAME
    Publication number: 20190248730
    Abstract: Aspects of the present disclosure include fatty acid ?-hydroxyester compounds (e.g., fatty acid esters of ?-hydroxybutyrate), fatty acid esters of butanediol, and pharmaceutically acceptable salts thereof. Also provided are pharmaceutical compositions having one or more fatty acid ?-hydroxyester compounds and/or one or more fatty acid esters of butanediol. Methods for treating a subject by administering one or more esters to the subject are also provided. Kits containing one or more of the subject esters are also described.
    Type: Application
    Filed: June 2, 2017
    Publication date: August 15, 2019
    Applicants: THE J. DAVID GLADSTONE INSTITUTES, ITHACA COLLEGE, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ITHACA COLLEGE
    Inventors: Eric Verdin, Scott Michael Ulrich, John C. Newman
  • Autoinducer molecule
    Patent number: 6936447
    Abstract: Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by Pseudomonas aeruginosa.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: August 30, 2005
    Assignees: University of Iowa Research Foundation, University of Rochester, Ithaca College
    Inventors: James P. Pearson, Kendall M. Gray, Luciano Passador, Kenneth D. Tucker, Anatol Eberhard, Barbara H. Iglewski, Everett P. Greenberg
  • Autoinducer molecule
    Patent number: 6057288
    Abstract: Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by Pseudomonas aeruginosa.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: May 2, 2000
    Assignees: University of Iowa, University of Rochester, Ithaca College
    Inventors: James P. Pearson, Kendall M. Gray, Luciano Passador, Kenneth D. Tucker, Anatol Eberhard, Barbara H. Iglewski, Everett P. Greenberg