Abstract: The invention relates to polysulfated glycosides of formula (I), the pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions containing these compounds as active ingredients. Furthermore the invention provides a method of preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders of the airways of mammals—including asthma and asthma-related pathologies.
Type:
Application
Filed:
January 25, 2011
Publication date:
May 19, 2011
Applicant:
Ivax Drug Research Institute Ltd.
Inventors:
János Kuszmann, István Kurucz, Gábor Medgyes, Nicholas Bodor
Abstract: The invention relates to sulfated oligosaccharides, more particularly to new pharmaceutical uses of sulfated oligosaccharides. The invention provides a method of preventing, treating or alleviating the symptoms of acute and chronic’, inflammatory disorders of the airways of mammals—including asthma and asthma-related pathologies. The invention further provides use of a sulfated oligosaccharide in the preparation of a medicament for the treatment of acute and chronic inflammatory disorders of the airways of mammals. The invention yet further provides use of a sulfated oligosaccharide to preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders of the airways of mammals—including asthma and asthma-related pathologies.
Type:
Application
Filed:
August 5, 2005
Publication date:
August 27, 2009
Applicant:
Ivax Drug Research Institute Ltd.
Inventors:
Janos Kuszmann, Istvan Kurucz, Gabor Medgyes, Nicholas Bodor
Abstract: The invention relates to new polysulfated glycosides of formula (I), the salts thereof formed with alkali metals or alkaline-earth metals, as well as the pharmaceutical compositions containing these compounds as active ingredients. Furthermore the invention provides a method of preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders of the airways of mammals—including asthma and asthma-related pathologies.
Type:
Application
Filed:
August 5, 2005
Publication date:
October 9, 2008
Applicant:
Ivax Drug Research Institute Ltd.
Inventors:
Janos Kuszmann, Istvan Kurucz, Gabor Medgyes, Nicholas Bodor
Abstract: The invention relates to polysulfated glycosides of formula (I), the pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions containing these compounds as active ingredients. Furthermore the invention provides a method of preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders of the airways of mammals—including asthma and asthma-related pathologies.
Type:
Application
Filed:
August 5, 2005
Publication date:
December 6, 2007
Applicant:
Ivax Drug Research Institute Ltd
Inventors:
Janos Kuszmann, Istvan Kurucz, Gabor Medgyes, Nicholas Bodor
Abstract: The invention relates to new 2,3-benzodiazepine derivatives of formula (I), isomers and acid addition salts thereof and to pharmaceutical compositions containing the same, as well as to pharmaceutical compositions and methods of using the same suitable for treating conditions associated with muscle spasms, epilepsy, acute and chronic forms of neurodegenerative diseases as well as preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders.
Type:
Grant
Filed:
February 4, 2003
Date of Patent:
February 22, 2005
Assignee:
IVAX Drug Research Institute, Ltd.
Inventors:
Sándor Sólyom, Gizella Ábrahám, Tamás Hámori, Pál Berzsenyi, Ferenc Andrási, István Kurucz
Abstract: Pyridazino(4,5-b)(1,5)oxazepinone, thiazepinone and diazepinone compounds of formula(I)
and their tautomers and the acid-addition salts of all these compounds show memory-enhancing and neuroprotective properties.
Type:
Grant
Filed:
November 15, 1999
Date of Patent:
August 5, 2003
Assignee:
IVAX Drug Research Institute, Ltd.
Inventors:
Ferenc Andrasi, Agnes Angyal nee Pataky, Pal Berzsenyi, Sandor Boros, Laszlo Harsing, Katalin Horvath, Peter Matyus, Imre Moravcsik, Agnes Papp nee Behr, Antal Simay, Erzsebet Szabo nee Bagdy, Katalin Szabo nee Pusztai, Istvan Tarnawa, Ildiko Varga