Patents Assigned to IXCELA, INC.
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Patent number: 11287417Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.Type: GrantFiled: June 9, 2021Date of Patent: March 29, 2022Assignee: IXCELA, INC.Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
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Patent number: 11287418Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's health based on the metabolite levels measured.Type: GrantFiled: June 9, 2021Date of Patent: March 29, 2022Assignee: IXCELA, INC.Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
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Patent number: 11287419Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.Type: GrantFiled: June 9, 2021Date of Patent: March 29, 2022Assignee: IXCELA, INC.Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
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Patent number: 11287420Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.Type: GrantFiled: June 9, 2021Date of Patent: March 29, 2022Assignee: IXCELA, INC.Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
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Patent number: 11122997Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.Type: GrantFiled: April 15, 2016Date of Patent: September 21, 2021Assignees: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke UniversityInventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
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Patent number: 11041847Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.Type: GrantFiled: April 27, 2020Date of Patent: June 22, 2021Assignee: IXCELA, INC.Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
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Patent number: 10278958Abstract: Provided is a method for reducing a potential for neurological damage of an animal at risk of head injury, by administering to the animal before exposure to the risk indole-3-propionic acid, indole lactic acid, or a salt, ester or protein complex or marginally bound preparation thereof, or a mixture thereof, in a suitable carrier.Type: GrantFiled: October 3, 2017Date of Patent: May 7, 2019Assignee: IXCELA, INC.Inventor: Wayne R. Matson
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Patent number: 10220066Abstract: A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically administering to the skin of a subject suffering from a virus-based disease of the skin a therapeutically amount of an aqueous, aqueous/alcohol, or natural plant oil extract of dandelion.Type: GrantFiled: June 22, 2018Date of Patent: March 5, 2019Assignee: IXCELA, INC.Inventor: Erika N. Angle
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Patent number: 10213468Abstract: A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically administering to the skin of a subject suffering from a virus-based disease of the skin a therapeutically amount of an aqueous, aqueous/alcohol, or natural plant oil extract of dandelion.Type: GrantFiled: June 22, 2018Date of Patent: February 26, 2019Assignee: IXCELA, INC.Inventor: Erika N. Angle
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Patent number: 10034908Abstract: A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically administering to the skin of a subject suffering from a virus-based disease of the skin a therapeutically amount of an aqueous, aqueous/alcohol, or natural plant oil extract of dandelion.Type: GrantFiled: June 11, 2015Date of Patent: July 31, 2018Assignee: IXCELA, INC.Inventor: Erika N. Angle
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Patent number: 10024842Abstract: Methods and devices for analyzing blood sample volumes are provided. In particular, the disclosure provides a method for estimating the volume of a blood sample on a substrate including the steps of acquiring an image of the blood sample. A coverage or area of the blood sample may be obtained from the image and compared to a standard curve to obtain a volume estimate of the blood sample. The disclosure also proves a device for scanning one or more blood samples on a substrate. The device includes three layers that may be assembled to hold multiple samples between the layers. The device also includes labels and may be disassembled for decontamination and reloading of samples.Type: GrantFiled: April 29, 2016Date of Patent: July 17, 2018Assignee: IXCELA, INC.Inventors: Samantha A. Matson, Beena E. Thomas, Swati Bhasin
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Publication number: 20180098722Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.Type: ApplicationFiled: April 15, 2016Publication date: April 12, 2018Applicants: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke UniversityInventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
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Patent number: 9744155Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.Type: GrantFiled: March 14, 2013Date of Patent: August 29, 2017Assignee: IXCELA, INC.Inventor: Wayne Matson
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Patent number: 9636325Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.Type: GrantFiled: April 16, 2015Date of Patent: May 2, 2017Assignee: IXCELA, INC.Inventor: Wayne R. Matson
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Patent number: 9603837Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.Type: GrantFiled: November 27, 2013Date of Patent: March 28, 2017Assignee: IXCELA, INC.Inventor: Wayne R. Matson