Patents Assigned to IXCELA, INC.
  • Patent number: 11287417
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Patent number: 11287418
    Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's health based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Patent number: 11287419
    Abstract: Methods and systems for evaluating health/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Patent number: 11287420
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: March 29, 2022
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Patent number: 11122997
    Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: September 21, 2021
    Assignees: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke University
    Inventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
  • Patent number: 11041847
    Abstract: Methods and systems for evaluating heath/disease state of an individual are provided herein. In particular, the disclosure provides methods for measuring levels of one or more metabolites of interest in an individual and using these measurements to assess the individual's health. The disclosure also provides systems for carrying out the disclosed methods. For example, the disclosed systems may include a metabolite level evaluation module to determine the individual's heath based on the metabolite levels measured.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: June 22, 2021
    Assignee: IXCELA, INC.
    Inventors: Wayne R. Matson, Samantha A. Matson, Erika N. Ebbel-Angle, Srikant Sarangi
  • Patent number: 10278958
    Abstract: Provided is a method for reducing a potential for neurological damage of an animal at risk of head injury, by administering to the animal before exposure to the risk indole-3-propionic acid, indole lactic acid, or a salt, ester or protein complex or marginally bound preparation thereof, or a mixture thereof, in a suitable carrier.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: May 7, 2019
    Assignee: IXCELA, INC.
    Inventor: Wayne R. Matson
  • Patent number: 10220066
    Abstract: A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically administering to the skin of a subject suffering from a virus-based disease of the skin a therapeutically amount of an aqueous, aqueous/alcohol, or natural plant oil extract of dandelion.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: March 5, 2019
    Assignee: IXCELA, INC.
    Inventor: Erika N. Angle
  • Patent number: 10213468
    Abstract: A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically administering to the skin of a subject suffering from a virus-based disease of the skin a therapeutically amount of an aqueous, aqueous/alcohol, or natural plant oil extract of dandelion.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: February 26, 2019
    Assignee: IXCELA, INC.
    Inventor: Erika N. Angle
  • Patent number: 10034908
    Abstract: A method for treatment of virus-based diseases of the skin, in particular, herpes simplex virus type-1 and herpes zoster, which comprises topically administering to the skin of a subject suffering from a virus-based disease of the skin a therapeutically amount of an aqueous, aqueous/alcohol, or natural plant oil extract of dandelion.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: July 31, 2018
    Assignee: IXCELA, INC.
    Inventor: Erika N. Angle
  • Patent number: 10024842
    Abstract: Methods and devices for analyzing blood sample volumes are provided. In particular, the disclosure provides a method for estimating the volume of a blood sample on a substrate including the steps of acquiring an image of the blood sample. A coverage or area of the blood sample may be obtained from the image and compared to a standard curve to obtain a volume estimate of the blood sample. The disclosure also proves a device for scanning one or more blood samples on a substrate. The device includes three layers that may be assembled to hold multiple samples between the layers. The device also includes labels and may be disassembled for decontamination and reloading of samples.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: July 17, 2018
    Assignee: IXCELA, INC.
    Inventors: Samantha A. Matson, Beena E. Thomas, Swati Bhasin
  • Publication number: 20180098722
    Abstract: Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein.
    Type: Application
    Filed: April 15, 2016
    Publication date: April 12, 2018
    Applicants: Mayo Foundation for Medical Education and Research, Ixcela Inc., Duke University
    Inventors: Balmiki Ray, Liewei Wang, Joanna Biernacka, Mark Frye, Richard M. Weinshilboum, Michiaki Kubo, Taisei Mushiroda, Wayne R. Matson, Rima Kaddurah-Daouk
  • Patent number: 9744155
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: August 29, 2017
    Assignee: IXCELA, INC.
    Inventor: Wayne Matson
  • Patent number: 9636325
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: May 2, 2017
    Assignee: IXCELA, INC.
    Inventor: Wayne R. Matson
  • Patent number: 9603837
    Abstract: Indole-3-propionic acid as a marker and for treatment for Huntington Disease.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: March 28, 2017
    Assignee: IXCELA, INC.
    Inventor: Wayne R. Matson