Abstract: An external patch that contains rupatadine as a second-generation antihistamine, has excellent plaster physical properties, good adhesion to applied skin, and good transdermal absorption of rupatadine as an active ingredient is provided. The external patch containing rupatadine uses an acrylic adhesive as an adhesive base. Specifically, the external patch containing rupatadine uses an acrylic adhesive as an adhesive base and further contains an organic acid having 2 to 7 carbon atoms as a solubilizer, a fatty acid ester as a softener, and/or a surfactant.
Type:
Grant
Filed:
April 18, 2018
Date of Patent:
November 23, 2021
Assignees:
TEIKOKU SEIYAKU CO., LTD., J.URIACH Y COMPANIA S.A.
Abstract: An external patch that contains rupatadine as a second-generation antihistamine, has excellent plaster physical properties, good adhesion to applied skin, and good transdermal absorption of rupatadine as an active ingredient is provided. The external patch containing rupatadine uses an acrylic adhesive as an adhesive base. Specifically, the external patch containing rupatadine uses an acrylic adhesive as an adhesive base and further contains an organic acid having 2 to 7 carbon atoms as a solubilizer, a fatty acid ester as a softener, and/or a surfactant.
Type:
Application
Filed:
April 18, 2018
Publication date:
April 23, 2020
Applicants:
TEIKOKU SEIYAKU CO., LTD., J.URIACH Y COMPANIA S.A.
Abstract: New compounds of formula (I) and the salts, solvates and prodrugs thereof, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.
Type:
Application
Filed:
February 27, 2004
Publication date:
July 27, 2006
Applicant:
J. URIACH Y COMPANIA S.A.
Inventors:
Carmen Almansa Rosales, Marina Virgili Bernado
Abstract: New phosphoramide derivatives of formula (I) and the salts and solvates thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful as antiinflammatory and analgesic agents.
Type:
Application
Filed:
December 23, 2003
Publication date:
May 25, 2006
Applicant:
J. Uriach Y Compania S.A.
Inventors:
Carmen Almansa Rosales, Javier Bartroliorpi
Abstract: The present invention relates to novel compounds of formula (I) and to the salts, solvates and prodrugs thereof, wherein the meanings of the various substituents are as disclosed in the description. Said compounds are useful for the treatment or prevention of psoriasis and other immune diseases.
Type:
Application
Filed:
July 17, 2003
Publication date:
December 1, 2005
Applicant:
J. Uriach y Compania S.A.
Inventors:
Javier Bartoli Orpi, Carmen Almansa Rosales, Alberto Fernandez De Arriba
Abstract: The present invention relates to new compounds of Formula (I) and the salts, solvates and prodrugs thereof, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as integrin ?4 antagonists.
Type:
Application
Filed:
April 8, 2003
Publication date:
June 30, 2005
Applicant:
J. Uriach Y CompaƱia S.A.
Inventors:
Elena Carceller Gonzalez, Jorge Salas Solana, Cristina Alvarez Farrerons, Juan Andreu Azanza