Abstract: A two layer prophylactic device taking the form of a male or female condom, or female diaphragm. The invention includes two latex layers bonded to one another along a spiral path which defines a corresponding spiral chamber between the latex layers. This spiral chamber extends between two compliant chambers at opposed ends of the device and is filled with a pharmacological fluid to help kill disease-bearing microbes and sperm cells which may permeate through the device during coitus. Due to the unique spiral chamber design leading between the complaint chambers, this pharmacological fluid remains uniformly dispersed during coitus and the device is less subject to rupture. Should one layer rupture during use, the pharmacological fluid will flow through the rupture and coat the adjacent sex organ. The present invention is especially effective in preventing unwanted pregnancies and the transmission of sexually transmitted diseases.