Patents Assigned to James Black Foundation Limited
  • Derivatives of aspartic acid and glutamic acid having anticholecystokinin activity
    Patent number: 5399748
    Abstract: Arylsulfonamide derivatives of .alpha.-amino dicarboxylic acids such as aspartic acid and glutamic acid posses anti-cholecystokinin activity. They are useful in the treatment of cholecystokinin-related disorders such as anorexia nervosa, pancreatic inflammation, biliary tract disease, Zollinger-Ellison syndrome and various psychiatric disorders, as well as in the potentiation of opiate analgesia, and in the treatment of certain cancers.
    Type: Grant
    Filed: January 12, 1993
    Date of Patent: March 21, 1995
    Assignee: James Black Foundation Limited
    Inventors: Howard B. Broughton, Sarkis B. Kalindjian, Caroline M. R. Low, Iain M. McDonald, Robert A. D. Hull, Nigel P. Shankley