Patents Assigned to James Cook University
  • Publication number: 20240174719
    Abstract: The present invention relates to proteins suitable for treating or preventing an inflammatory or autoimmune condition, pharmaceutical compositions comprising same, and methods of use comprising same.
    Type: Application
    Filed: March 17, 2022
    Publication date: May 30, 2024
    Applicant: James Cook University
    Inventors: Alexander Constantine Loukas, Paul Robert Giacomin, Stephanie Margaret Ryan, Roland Ruscher
  • Patent number: 11976108
    Abstract: A modified Ac-TMP-2 protein lacks one or a plurality of acidic C-terminal amino acids normally present in a full-length or wild-type Ac-TMP-2 protein and may also lack one or a plurality of N-terminal amino acids while retaining the amino acid sequence C-S-C at or near the N-terminus. The modified Ac-TMP-2 protein may be useful in method and composition for reducing or alleviating inflammation in a subject. Inflammation may be associated with a disease is a disease of the digestive tract such as chronic gastritis or an inflammatory bowel disease such as Crohn's disease or ulcerative colitis, or a disease of the respiratory system, such as asthma, emphysema, chronic bronchitis, and chronic obstructive pulmonary disease.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: May 7, 2024
    Assignee: James Cook University
    Inventors: Alex Loukas, Andrew Leech, Darren Pickering
  • Patent number: 11883449
    Abstract: The present invention relates to a method of reducing total gas production and/or methane production in a ruminant animal.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: January 30, 2024
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Meat & Livestock Australia Limited, James Cook University
    Inventors: Lorenna Machado, Marie Elisabeth Magnusson, Nigel William Tomkins, Robert Douglas Kinley, Peter Canisius Denys, Nicholas Andrew Paul
  • Publication number: 20210077555
    Abstract: The present invention relates to a method of reducing total gas production and/or methane production in a ruminant animal.
    Type: Application
    Filed: November 24, 2020
    Publication date: March 18, 2021
    Applicants: Commonwealth Scientific and Industrial Research Organisation, Meat & Livestock Australia Limited, James Cook University
    Inventors: Lorenna MACHADO, Marie Elisabeth MAGNUSSON, Nigel William TOMKINS, Robert Douglas KINLEY, Peter Canisius DENYS, Nicholas Andrew PAUL
  • Patent number: 10881697
    Abstract: The present invention relates to a method of reducing total gas production and/or methane production in a ruminant animal.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: January 5, 2021
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Meat & Livestock Australia Limited, James Cook University
    Inventors: Lorenna Machado, Marie Elisabeth Magnusson, Nigel William Tomkins, Robert Douglas Kinley, Peter Canisius Denys, Nicholas Andrew Paul
  • Patent number: 9980995
    Abstract: The present invention relates to a method of reducing total gas production and/or methane production in a ruminant animal.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: May 29, 2018
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Meat & Livestock Australia Limited, James Cook University
    Inventors: Lorenna Machado, Marie Elisabeth Magnusson, Nigel William Tomkins, Robert Douglas Kinley, Peter Canisius Denys, Nicholas Andrew Paul
  • Publication number: 20160229905
    Abstract: A modified Ac-TMP-2 protein lacks one or a plurality of acidic C-terminal amino acids normally present in a full-length or wild-type Ac-TMP-2 protein and may also lack one or a plurality of N-terminal amino acids while retaining the amino acid sequence C—S—C at or near the N-terminus. The modified Ac-TMP-2 protein may be useful in method and composition for reducing or alleviating inflammation in a subject. Inflammation may be associated with a disease is a disease of the digestive tract such as chronic gastritis or an inflammatory bowel disease such as Crohn's disease or ulcerative colitis, or a disease of the respiratory system, such as asthma, emphysema, chronic bronchitis, and chronic obstructive pulmonary disease.
    Type: Application
    Filed: September 18, 2014
    Publication date: August 11, 2016
    Applicant: James Cook University
    Inventors: Alex Loukas, Andrew Leech, Darren Pickering
  • Patent number: 8293093
    Abstract: A method of electrowinning or electrorefining copper from a copper electrolyte solution which contains chloride ions, the method comprising the steps of: (a) forming a polyacrylamide solution by dissolving polyacrylamide, having a molecular weight range of 5,000 to 20,000,000 Daltons, in an acidic medium and under conditions to form a polyacrylamide block copolymer having blocks of carboxyl groups dispersed along the polymer backbone; (b) introducing the polyacrylamide solution into an electrolytic cell containing the copper electrolyte solution at a polyacrylamide concentration of 0.01-10 mg/L; and (c) electroplating copper from the copper electrolyte solution to form a copper cathode.
    Type: Grant
    Filed: August 23, 2005
    Date of Patent: October 23, 2012
    Assignee: James Cook University
    Inventors: Cesimiro Paulino Fabian, Thomas William Lancaster, Natalie Lancaster, legal representative
  • Publication number: 20110129935
    Abstract: The invention relates to methods and compositions for assessing protein stability, including improved assays for distinguishing between soluble and aggregated proteins. The methods and compositions include measuring residual fluorescence of a fusion protein in a soluble fraction as an indicator of protein solubility, and monitoring fluorescence quenching of a fusion protein as an indicator of protein stability. The fusion protein may comprise an amino acid sequence of a protein of interest, a peptide linker amino acid sequence and an amino acid sequence of a fluorescent marker protein.
    Type: Application
    Filed: December 2, 2010
    Publication date: June 2, 2011
    Applicant: James Cook University
    Inventor: Patrick Schaeffer
  • Patent number: 6500632
    Abstract: An assay to screen potential inhibitors of the C4 acid cycle in plants. The assay involves testing inhibition of C4 enzymes by incubating a mixture that includes pyruvate orthophosphate dikinase, phosphoenolpyruvate carboxylase and malate dehydrogenase and their substrates with a potential inhibitor. Detection of inhibition depends on comparing the resulting levels of NADH or NAD+ in the test mixture to the levels of NADH or NAD+ in a control.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: December 31, 2002
    Assignees: Australian Institute of Marine Science, James Cook University of North Queensland
    Inventors: James Nigel Burnell, Lyndon Edwin Llewellyn
  • Patent number: 5823800
    Abstract: An electrical socket is formed in a printed circuit board (PCR) using standard automated PCB production techniques. The socket (20) comprises a respective three legged slotted aperture (22) for each pin (11) of a male plug. The slotted aperture (22) defines two cantilevered portions (23) which receive a respective pin (11) in A slot defined therebetween. The slot is of slightly narrower width than the corresponding pin (11), but the cantilevered portions (23) are resiliently movable to enable the slot to receive and frictionally retain the pin therein. Plated contact surfaces are formed on either side of the slot to make physical and electrical contact with the pin. A modified socket (40) includes an integrally formed isolation switch. The cantilevered portions (41) extend beyond the point where the pin (11) is inserted therebetween.
    Type: Grant
    Filed: November 25, 1996
    Date of Patent: October 20, 1998
    Assignee: James Cook University of North Queensland
    Inventors: Harry Suehrcke, Noel Wilhelmus Lovisa
  • Patent number: 5032794
    Abstract: Changes in underwater sediment level in a marine environment are monitored electronically using a probe embedded in the sediment. The probe includes an electrical current source to generate an electric field extending across the sediment interface. Voltage measurements are taken at at least three sensors on the probe whose positions are known relative to the current source. The height of the sediment interface relative to the current source can then be calculated, and logged, and changes in sediment level can be monitored. The conductivities of the sediment and seawater can also be calculated by taking additional voltage measurements.
    Type: Grant
    Filed: May 7, 1990
    Date of Patent: July 16, 1991
    Assignees: James Cook University of Northern Queensland, Australian Institute of Marine Science
    Inventors: Peter V. Ridd, John L. Nicol, Eric Wolanski