Abstract: A novel compound, and stable compositions thereof for the effective, nonirritating treatment of microbial colonization are disclosed. The compound is used for the topical treatment of affected areas as well as for control of certain diarrheas. The compound is the ozonide of the liquid wax jojoba oil. The ozonide material of the present invention has the ability to release nascent oxygen directly to locales to at least inhibit the microorganisms without the characteristic dryness and skin irritation associated with previous benzoyl peroxide treatments. The compositions are stable, in contrast to the limited shelf-stability of the previously used benzoyl peroxide formulation. This ozonide and products containing same have no tendency to become rancid, which is a problem with other ozonides.