Patents Assigned to James Madison University
  • Patent number: 10905112
    Abstract: An animal monitoring station comprises a housing, a bait receptacle, a camera, a scale, and a grid. The housing comprises a chamber; and at least one port configured to allow an animal: free ingress to the chamber; and free egress to the chamber. The bait receptacle is disposed inside the chamber. The camera is disposed in the chamber. The scale is disposed in a field of view of the camera. A grid is disposed in the field of view.
    Type: Grant
    Filed: February 3, 2019
    Date of Patent: February 2, 2021
    Assignee: JAMES MADISON UNIVERSITY
    Inventors: Katrina E Gobetz, Bryan Cage
  • Patent number: 7381471
    Abstract: The present invention is directed to improved microdevices and methods of manufacturing such devices. More particularly the present invention is directed to the use of a compound having the general structure (formula (I)): wherein R is selected from the group consisting of C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, and C5-C6 aryl for bonding silica based substrates to plastic substrates or to other silica based substrates.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: June 3, 2008
    Assignees: University of Virginia Patent Foundation, James Madison University
    Inventors: Brian H. Augustine, James P. Landers, Jerome P. Ferrance, Joy M. Polefrone, W. Christopher Hughes
  • Patent number: 6117658
    Abstract: The PHA biosynthetic pathway is combined with a succinic semialdehyde metabolic pathway that metabolizes succinic semialdehyde via a 4-hydroxybutyryl-CoA intermediate in order to produce high levels of PHA comprising 4HB monomer units. This combination is particularly useful, in part, because the PHA biosynthetic pathway is well known and has been expressed to produce P(3HB) to levels as high as 70-80% of the cell dry weight, while the succinic semialdehyde metabolic pathway is also well known, and the combination of the two pathways means that production of PHAs comprising 4HB monomer units does not depend on immediate precursors of 4-hydroxybutyrate. Rather, the production of the PHAs comprising 4HB monomer units can occur simply from the extraction of succinate or succinyl-CoA from the citric acid cycle when the host cell is grown on an inexpensive carbon source such as glucose.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: September 12, 2000
    Assignee: James Madison University
    Inventors: Douglas E. Dennis, Henry E. Valentin
  • Patent number: 5512456
    Abstract: Poly-.beta.-hydroxybutyrate is produced by providing a culture of Escherichia coli bacterial host cells transformed by a DNA sequence coding for the biosynthetic pathway of poly-.beta.-hydroxybutyrate and a DNA sequence coding for the lysozyme gene; growing the culture and obtaining expression of the poly-.beta.-hydroxybutyrate biosynthetic pathway and the lysozyme gene in each Escherichia coli bacterial host cell; lysing the Escherichia coli bacterial host cells and collecting the poly-.beta.-hydroxybutyrate. An Escherichia coli HMS174(p4A BstB!, pLysS) deposited with the American Type Culture Collection under Accession No. 69001, comprising a plasmid containing a biosynthetic pathway coding for poly-.beta.-hydroxybutyrate and a plasmid containing a lysozyme gene is disclosed.
    Type: Grant
    Filed: May 29, 1992
    Date of Patent: April 30, 1996
    Assignee: James Madison University
    Inventor: Douglas E. Dennis
  • Patent number: 5371002
    Abstract: The invention related to recombinant deoxyribonucleic acid (DNA) technology and, more particularly, to a process whereby poly-beta-hydroxyalkanoate (PHA) copolymers can be synthesized in a recombinant host strain containing the poly-beta-hydroxybutyrate (PHB) biosynthetic genes of Alcaligenes eutrophus.
    Type: Grant
    Filed: September 27, 1991
    Date of Patent: December 6, 1994
    Assignee: James Madison University
    Inventors: Douglas E. Dennis, Steven C. Slater