Patents Assigned to Japan as Represented by Director General of Agency of National Cancer Center
  • Method of inhibiting intestinal polyps
    Patent number: 7572775
    Abstract: The present invention provides a method for reducing the occurrence and progress of intestinal polyps that may develop into colon cancer, and a carboxylic acid amide compound as an active component to reduce intestinal polyps, represented by the following Formula: wherein R is a lower alkyl group and X is a halogen an example being 4-diethoxyphosphinoylmethyl-N-(4-bromo-2-cyanophenyl) benzamide.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: August 11, 2009
    Assignees: Japan as Represented by Director General of Agency of National Cancer Center, Otsuka Pharmaceutical Factory, Inc.
    Inventors: Keiji Wakabayashi, Michihiro Mutoh
  • Intestinal Polyp Inhibitor
    Publication number: 20080139516
    Abstract: The present invention provides a medicine that has the effect of preventing the occurrence, inhibiting the progress and treatment of intestinal polyps that may develop into colon cancer, and relates to an intestinal polyp suppressor containing as an active component a carboxylic acid amide compound represented by the following General Formula: (wherein R is a lower alkyl group and X is a halogen), and in particular 4-diethoxyphosphinoylmethyl-N-(4-bromo-2-cyanophenyl)benzamide.
    Type: Application
    Filed: September 30, 2005
    Publication date: June 12, 2008
    Applicants: JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF NATIONAL CANCER CENTER, OSTUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Keiji Wakabayashi, Michihiro Mutoh
  • COMPOSITION FOR DEAMINATING DNA AND METHOD OF DETECTING METHYLATED DNA
    Publication number: 20080070240
    Abstract: (1) A sulfite composition having a sulfite concentration of more than 6.2 M, (2) a method for deaminating DNA using a sulfite composition described in (1), (3) a method for detecting methylated DNA using a sulfite composition described in (1), (4) a kit for deaminating DNA or for detecting methylated DNA comprising a sulfite composition described in (1).
    Type: Application
    Filed: September 18, 2006
    Publication date: March 20, 2008
    Applicants: Toyo Boseki Kabushiki Kaisha, Japan as Represented by Director General of Agency of National Cancer Center
    Inventors: Hikoya HAYATSU, Kazuo NEGISHI, Masahiko SHIRAISHI