Patents Assigned to Japan Finechem Company, Inc.
  • PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE
    Publication number: 20200181091
    Abstract: The present invention relates to a method of producing a pyrazole-4-carboxamide derivative including subjecting a pyrazole-4-carboxylic acid ester and an amine to an aminolysis reaction in a solvent in the presence of a base, provided that the reaction is completed without removing a by-produced alcohol or phenol outside the system. An industrial production method of a pyrazole-4-carboxamide derivative which is useful as an agricultural fungicide, simply and in high yield and high purity as compared with the conventional method, is provided.
    Type: Application
    Filed: July 23, 2018
    Publication date: June 11, 2020
    Applicant: JAPAN FINECHEM COMPANY, INC.
    Inventors: Yusuke KURIHARA, Koki SATO, Ayase WASUZU, Yu YAMADA
  • Process for producing 1-substituted-3-fluoroalkylpyrazole-4-carboxylate
    Patent number: 7863460
    Abstract: In a process for producing 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylate (3) by a reaction of 2-alkoxymethylenefluoroacylacetate (1) and hydrazine (2), the reaction is conducted in the presence of a base and water, to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3) with high selectivity and yield. This novel process enables to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3), which is useful as an intermediate for pharmaceuticals and agrochemicals, with high selectivity and yield by simple and safe operations.
    Type: Grant
    Filed: February 23, 2006
    Date of Patent: January 4, 2011
    Assignees: Sagami Chemical Research Center, Japan Finechem Company, Inc.
    Inventors: Hidenori Aihara, Wakako Yokota, Tetsu Yamakawa, Kenji Hirai
  • Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate
    Publication number: 20080154045
    Abstract: In a process for producing 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylate (3) by a reaction of 2-alkoxymethylenefluoroacylacetate (1) and hydrazine (2), the reaction is conducted in the presence of a base and water, to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3) with high selectivity and yield. This novel process enables to produce 1-substituted-3-fluoroalkylpyrazole-4-carboxylate (3), which is useful as an intermediate for pharmaceuticals and agrochemicals, with high selectivity and yield by simple and safe operations.
    Type: Application
    Filed: February 23, 2006
    Publication date: June 26, 2008
    Applicants: Sagami Chemical researckh Center, Japan Finechem Company, INC.
    Inventors: Hidenori Aihara, Wakako Yokota, Tetsu Yamakawa, Kenji Hirai