Abstract: An inhalation device controller is configured to control an atomizer including a container configured to hold an aerosol source of a liquid, a heater, and a transport portion configured to transport the aerosol source from the container to a heating area by the heater. The controller includes a control circuit configured to monitor a physical amount correlated with a temperature of the heater and configured to control power to be supplied to the atomizer such that the physical amount under monitoring approaches a target value. The target value is set such that the temperature of the heater during heating of the aerosol source falls within a range of 210° C. to 230° C.

Abstract: Provided is an agent for the treatment or prophylaxis of inflammatory diseases, allergic diseases, autoimmune diseases, transplant rejection or the like. A compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein each symbol is as described in the specification.

Abstract: An inhalation device controller includes a holder that holds an atomizer including a heater for atomizing an aerosol source, and a processor. Upon detecting an atomization request, the processor executes first determination processing of determining a remaining amount of the aerosol source in the atomizer using a first algorithm, and upon detecting an atomization request after the execution of the first determination processing, executes second determination processing of determining presence/absence of the aerosol source in the atomizer using a second algorithm. Even if it is determined by the first determination processing that the remaining amount is larger than 0, if aerosol source absence is determined by the second determination processing, the processor outputs the aerosol source absence as a final determination result, and inhibits a supply of power to the heater.

Abstract: An inhalation device controller includes a holding portion configured to hold an atomizer including a heater configured to heat an aerosol source, a power supply unit configured to supply power to the heater of the atomizer attached to the holding portion, an amplifier to which a voltage according to a voltage of a node on a current path configured to supply the power to the heater is input, and a processor configured to acquire information from the amplifier and execute control according to the information. A first range that a value of the information takes in a holding state in which the holding portion holds the atomizer and a second range that the value of the information takes in a non-holding state in which the holding portion does not hold the atomizer do not include ranges overlapping each other.

Abstract: The present invention provides a controller for an inhalation device, comprising: a power supplier configured to supply power to a heater used to heat and atomize an aerosol source; a detection circuit configured to detect a resistance value of the heater; and a processor configured to execute heating processing of heating the aerosol source by controlling the power supplier in accordance with reception of an atomization request of the aerosol source, wherein the processor controls the heating processing based on the resistance value of the heater detected using the detection circuit, a reference temperature of the heater, and a reference resistance value of the heater, and updates the reference resistance value by the resistance value of the heater detected using the detection circuit after an end of the heating processing and before the reception of the next atomization request.

Abstract: An inhalation device controller includes a power supply unit configured to supply power to an atomizer including a heater configured to heat an aerosol source, a detection circuit configured to detect a resistance value of the heater, a processor configured to generate a control signal in accordance with a smoothed signal generated by smoothing information obtained using the detection circuit, and a holding portion configured to hold the atomizer in a detachable state. The holding portion includes a first electrical contact contacting a third electrical contact of the atomizer, and a second electrical contact contacting a fourth electrical contact of the atomizer. Information obtained using the detection circuit is affected by stress applied to the first to fourth electrical contacts when attaching the atomizer to the holding portion.

Abstract: A power supply unit for an aerosol inhaler includes a power supply dischargeable to a load for heating an aerosol generation source, a first sensor configured to output a signal indicating an aerosol generation request, and a processing device configured to acquire the signal. The processing device causes the power supply unit to operate in a first mode in which a maximum power consumption amount is a first amount and a second mode in which a maximum power consumption amount is smaller than the first amount, causes the power supply unit to operate in the second mode when a period during which the signal is not acquired exceeds a predetermined time in the first mode, and causes the power supply unit to operate such that a maximum power consumption amount is less than the first amount at a timing before the period exceeds the predetermined time in the first mode.

Abstract: A power supply unit for an aerosol inhaler, which includes a power supply configured to discharge electricity to a load that is configured to heat an aerosol generation source and has a correlation between temperature and electric resistance values, includes: a first element connected in series to the load and having a first electric resistance value; a second series circuit that includes a second element having a second electric resistance value, and a third element connected in series to the second element and having a third electric resistance value, the second series circuit being connected in parallel with a first series circuit including the load and the first element; and an operational amplifier connected to the first series circuit and the second series circuit. The first electric resistance value is less than an electric resistance value of the load.

Abstract: A power supply unit for an aerosol inhaler includes: a first series circuit; a second series circuit connected in parallel with the first series circuit; a first operational amplifier including a non-inversion input terminal connected to one of a first node and a second node, and an inversion input terminal connected to the other of the first node and the second node; and an adjustment circuit connected to the first operational amplifier and configured to prevent a differential input value of the first operational amplifier from being equal to a potential of a negative power supply terminal of the first operational amplifier or a minimum value acquirable by the first operational amplifier, in a state where a potential of the node connected to the non-inversion input terminal is less than a potential of the node connected to the inversion input terminal.

Abstract: The present invention aims to provide a new method for producing an indole compound or a salt thereof, which has an ITK inhibitory action, and is useful for the prophylaxis or treatment of inflammatory disease.

Abstract: A power supply unit for an aerosol inhaler that causes an aerosol generated from an aerosol source to pass through a flavor source to add a flavor component of the flavor source to the aerosol includes a power supply configured to be dischargeable to a first load configured to heat the aerosol source, and a processing device configured to determine a remaining amount of a flavor component contained in the flavor source based on a time of discharging from the power supply to the first load and a variable different from the time in a period during which the discharging is performed.

Abstract: A power supply unit for an aerosol inhaler that causes an aerosol generated from an aerosol source to pass through a flavor source to add a flavor component of the flavor source to the aerosol includes a power supply configured to be dischargeable to a first load configured to heat the aerosol source and a processing device. The processing device is configured to control discharging from the power supply to the first load in response to a signal from a sensor indicating an aerosol generation request, and the processing device is configured to control the discharging such that a unit flavor amount converges to a target amount based on an output of an element configured to output information on a temperature of the flavor source, the unit flavor amount being an amount of a flavor component added to an aerosol generated for each aerosol generation request.

Abstract: A power supply unit for an aerosol inhaler that causes an aerosol generated from an aerosol source to pass through a flavor source to add a flavor component of the flavor source to the aerosol includes a power supply configured to be dischargeable to a first load configured to heat the aerosol source, and a processing device configured to cause determined power to be discharged from the power supply to the first load in response to a signal from a sensor configured to output the signal indicating an aerosol generation request. The processing device is configured to determine the power based on a time of discharging and a variable different from the time in discharging from the power supply to the first load in response to the signal before a previous time.

Abstract: A power supply unit for an aerosol inhaler that causes an aerosol generated from an aerosol source heated by a first load to pass through a flavor source heated by a second load to add a flavor component of the flavor source to the aerosol includes a power supply dischargeable to the first load and the second load and a processing device. The processing device is configured to control discharging to the first load in response to a signal indicating an aerosol generation request, to control discharging to the second load such that a temperature of the flavor source converges to a target temperature based on information on a temperature of the flavor source, and to increase the target temperature based on a cumulative number of times of discharging to the first load or a cumulative time of discharging to the first load in response to the signal.

Abstract: A power supply unit for an aerosol inhaler that causes an aerosol generated from an aerosol source heated by a first load to pass through a flavor source heated by a second load connected in parallel to the first load to add a flavor component of the flavor source to the aerosol includes a power supply configured to be dischargeable to the first load and the second load, and a first boosting circuit connected between the power supply and the first load.

Abstract: A flavor aspirator includes: a weight-concentrated part that is provided at a position off the mouthpiece end and closer to the mouthpiece end side than to a midpoint position between the mouthpiece end and the distal end, and that accounts for at least approximately half of a total weight of the flavor aspirator. A value of (a length from the mouthpiece end to the center of gravity)/(a total length defined by a length from the mouthpiece end to the distal end) is in a range of 0.20 to 0.45.

Abstract: A power supply unit of an aerosol generation apparatus includes: a power supply capable of discharging to a load for generating an aerosol from an aerosol source; a controller configured to control the power supply; a housing configured to house the power supply and the controller; and a plurality of sensors capable of outputting the same physical quantity inside the housing. The controller is configured to diagnose a state of the power supply unit based on outputs of the plurality of sensors.

Abstract: A non-combustible heating-type smoking article includes: a tobacco part. The tobacco part includes: a tobacco filler; and a wrapper enclosing the tobacco filler. The tobacco part has a hardness of 0.41 to 1.5 N when compressed by a length corresponding to 10% of a diameter of the tobacco part in a diameter direction of the tobacco part. The wrapper is formed by attaching two or more sheets. The wrapper has a tensile strength of 10 to 30 N in a transverse direction crossing an axial direction of the tobacco part.

Abstract: A power supply unit for an aerosol inhaler includes: a power supply that is able to discharge power to a load for generating an aerosol from an aerosol generation source; and a control unit that is configured to control at least one of charging and discharging of the power supply such that the power supply does not become one or both of a fully charged state and a discharging termination state.

Abstract: A power supply unit for an aerosol inhaler includes: a power supply that is able to discharge power to a load for generating an aerosol from an aerosol generation source; and a control unit that is configured to control at least one of charging and discharging of the power supply such that the power supply does not become one or both of a fully charged state and a discharging termination state.