Patents Assigned to Japanese Foundation for Cancer Research Cancer Institute
  • Diagnosis for mutant APC by immunoassay
    Patent number: 6413727
    Abstract: A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: July 2, 2002
    Assignees: The Johns Hopkins University, University of Utah, Japanese Foundation for Cancer Research Cancer Institute, Zeneca Limited
    Inventors: Hans Albertsen, Rakesh Anand, Mary Carlson, Joanna Groden, Philip John Hedge, Geoff Joslyn, Kenneth Kinzler, Alexander Fred Markham, Yusuke Nakamura, Andrew Thliveris, Bert Vogelstein, Raymond L. White
  • Detection of inherited and somatic mutations of APC gene in colorectal cancer of humans
    Patent number: 5648212
    Abstract: Methods are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. APC is a tumor suppressor.
    Type: Grant
    Filed: August 12, 1994
    Date of Patent: July 15, 1997
    Assignees: The John Hopkins University, University of Utah, Japanese Foundation for Cancer Research Cancer Institute, Zeneca Limited
    Inventors: Hans Albertsen, Rakesh Anand, Mary Carlson, Joanna Groden, Philip John Hedge, Geoff Joslyn, Kenneth Kinzler, Alexander Markham, Yusuke Nakamura, Andrew Thliveris, Bert Vogelstein, Raymond L. White