Abstract: The present disclosure discloses a compound of Formula (I) and its polymorphs, stereoisomers, prodrugs, solvates, co-crystals, intermediates, pharmaceutically acceptable salts, and metabolites thereof and a process of preparation of compounds of Formula (I). The present disclosure also discloses a method of treatment of a condition mediated by aggregation of A?42, tau, or ?-syn. The present disclosure also discloses a compound of Formula (I) that provides reversal or improvement of cognitive decline.

Abstract: The present disclosure refers to increasing the catalytic efficiency of Weyl semimetals by subjecting Weyl semimetals to an external magnetic field of greater than 0 T, for example greater than 0.1 T. In a preferred embodiment of the present disclosure the Weyl semimetal is selected from the group consisting of NbP, TaP, NbAs and TaAs.

Abstract: The present disclosure relates to compounds which function as small molecule fluorescent probes which aid in recognition of specific sequences in DNA and detection of A? aggregates. Probes/dyes of the instant disclosure are specific to AT-rich sequences of DNA and A? aggregates. These small organic dyes/probes are capable of exhibiting switch-on fluorescence and play an important role in fluorescence spectroscopy, diagnostics, imaging and biomedical applications.

Abstract: The present disclosure relates to the field of pharmaceutical chemistry and biotechnology. The present disclosure also relates to a compound of Formula I and a process of preparation thereof. The disclosure furthermore relates to methods/use of Formula I compounds as DNA probes. Said Formula I compounds are employed for recognizing specific DNA sequences by near Infra-red (NIR)-Fluorescence Switch-on mechanism, and have related applications including but not limited to cell imaging. Also, method of treating parasitic infections by employing the present compound of Formula I is provided.

Abstract: The present disclosure provides compositions comprising colloidal matter in solvent, employed for crackle formation when exposed to surface of a substrate. The said compositions crackle spontaneously without any external stimuli when exposed to the substrate surface as a film. The present disclosure also relates to substrates having a film by exposure to said composition and a method of preparing said substrate. The present disclosure also relates to patterned substrates fabricated with material or energy inputs deposited in template formed by crackling of the film and a method of preparing said patterned substrate and a kit for obtaining such substrates. The present disclosure also relates to using the said substrates for various applications specifically in the field of electronics or optoelectronics.

Abstract: The present disclosure relates to the field of synthetic pharmaceutical chemistry and biology. The disclosure provides a compound of Formula I and a process of preparation thereof. The disclosure further relates to methods and use of Formula I compounds as stimuli-responsive probes. Said Formula I compounds are employed for detecting and quantifying reactive oxygen species (ROS), and have related applications including but not limited fluorescence spectroscopy, diagnostics, treatment, imaging and biomedical applications.

Abstract: The present disclosure relates to the field of synthetic pharmaceutical chemistry and biology. The disclosure provides a compound of Formula I and a process of preparation thereof. The disclosure further relates to methods and use of Formula I compounds as stimuli-responsive probes. Said Formula I compounds are employed for detecting and quantifying reactive oxygen species (ROS), and have related applications including but not limited fluorescence spectroscopy, diagnostics, treatment, imaging and biomedical applications.

Abstract: Aromatic diimide chromophores and methods for using the chromophores for the detection of volatile organic compounds are described. The chromophores are able to reversibly change colors in the presence or absence of volatile organic compounds.

Abstract: Sorbent polymers which are selective to taking up hydrocarbons are provided for separating hydrocarbons from fluids and taking up hydrocarbons from off of and intermixed with solid materials. The hydrocarbons may at least partially be expressed out of and recovered from the polymer by squeezing. The polymers may be re-used for picking up additional hydrocarbons. Methods for producing and using the polymers are also provided.

Abstract: The present disclosure relates to the field of medicinal chemistry and more particularly to the development of antimicrobial compounds. The disclosure relates to the synthesis and characterization of compounds comprising aromatic radical or an aliphatic radical, an alkyl amine and amino acid moiety wherein said compounds exhibit antimicrobial activity against various drug-sensitive and drug-resistant pathogenic 10 microorganisms.

Abstract: The present disclosure relates to polyamine conjugates, its isomers, prodrugs and pharmaceutically acceptable salts thereof. The present disclosure also relates to process of preparation of polyamine conjugates, its stereoisomers, prodrugs, pharmaceutically acceptable salts thereof, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases mediated by microbes.

Abstract: The present disclosure relates to compounds which function as small molecule fluorescent probes which aid in recognition of specific sequences in DNA and detection of A? aggregates. Probes/dyes of the instant disclosure are specific to AT-rich sequences of DNA and A? aggregates. These small organic dyes/probes are capable of exhibiting switch-on fluorescence and play an important role in fluorescence spectroscopy, diagnostics, imaging and biomedical applications.

Abstract: The present disclosure relates to the development of antibacterial compounds and their nanoparticle compositions. Methods of making the compounds and their nanoparticle compositions, their use as medicament for the treatment of bacterial infection and also for suppressing potentially harmful inflammation are disclosed.

Abstract: Implementations and techniques for manufacturing strain sensitive sensors and/or strain resistant conduits from a metal and carbon matrix are generally disclosed.

Abstract: Methods and devices for preparing microscale polymer relief structures from a thin polymer layer on an absorbing substrate are described. The described methods are ultrafast (about 8 nanoseconds) and allow formation of patterned microstructures having complex morphologies and narrow line widths that are an order of magnitude smaller than the masks used in the methods.

Abstract: The present invention relates to non toxic, immunogenic viral Tat DNA sequences comprising wherein the Tat Sequence is rendered non toxic and immunogenic by insertion of T-Helper Epitope into the Cysteine-rich domain, or Basic domain or Core domain of said Tat DNA sequence, optionally along with insertion of a synthetic Intron between C-terminal region and Exon II region of the Tat DNA Sequence. The present invention also relates to elongation factor promoter constructs and process thereof. Also the present invention relates to a process of obtaining the non toxic and immunogenic Tat DNA sequence and vaccine and a method thereof.

Abstract: Sorbent polymers which are selective to taking up hydrocarbons are provided for separating hydrocarbons from fluids and taking up hydrocarbons from off of and intermixed with solid materials. The hydrocarbons may at least partially be expressed out of and recovered from the polymer by squeezing. The polymers may be re-used for picking up additional hydrocarbons. Methods for producing and using the polymers are also provided.

Abstract: Aromatic diimide chromophores and methods for using the chromophores for the detection of volatile organic compounds are described. The chromophores are able to reversibly change colors in the presence or absence of volatile organic compounds.

Abstract: Aromatic diimide chromophores and methods for using the chromophores for the detection of volatile organic compounds are described. The chromophores are able to reversibly change colors in the presence or absence of volatile organic compounds.

Abstract: The present invention relates to identification of centromeric sequences of Candida dubliniensis and localization of CdCse4p centromeric histone to the identified region. Also the present invention relates to distinguishing Candida dubliniensis from other members of genus Candida.