Abstract: A tight device including a flange joined to an enclosure to connect interior and exterior of the enclosure via a through opening of the flange, a door moving between closed and open configurations, and a joint integral with the flange and joining the through opening from the door in the closed configuration. To limit risk of pollution when transferring sterile material through the device, a tubular member is mounted on the flange to move between a retracted position, where the tubular member is arranged outside the through opening when the door is in the closed configuration, and a deployed position, where the tubular member is arranged in the through opening so as to cover the joint when the door is in the open configuration. An elastic member drives the tubular member from its retracted to its deployed position when the door is in the open configuration.

Abstract: A disposable isolator including a bottom, a flexible peripheral wall defining a clean and sterile inner volume, a first pair of joining parts forming a first tight junction at the bottom, this first pair including an inner part placed inside the inner volume and suitable for positioning containers, and an outer part placed outside the inner volume and suitable for cooperating by shape matching with a positioning cavity provided on a support table, and a second pair of joining parts forming a second tight junction at the peripheral wall and including an outer part suitable for being connected to a robot, and an inner part suitable for being connected to a manipulating tool, the first and second pairs being designed so that the robot applies the manipulating tool on the containers positioned on the support table.