Patents Assigned to Jean Kadouche
  • Multispecific antigens binding fragments and multispecific antibodies
    Patent number: 11945879
    Abstract: The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: April 2, 2024
    Assignees: Jean Kadouche, Centre National de la Recherche Scientifique, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, University of Lausanne
    Inventors: Jean Kadouche, Jean-Pierre Mach, Olivier Michielin, Vincent Zoete, Justyna Iwaszkiewicz, Martine Cerutti, Sylvie Choblet, Josee Golay