Abstract: A purpose is to provide a vaccine which can prevent porcine edema disease in farms where porcine edema disease is anticipated. Meeting this purpose is a vaccine that is a fusion protein in which Stx2eB and a polypeptide having a coiled-coil forming unit are joined or a multimer of the fusion protein, and by immunizing pigs with this vaccine, it is possible to induce potent neutralizing antibodies and to defend against the onset of porcine edema disease.
Type:
Grant
Filed:
October 18, 2013
Date of Patent:
July 11, 2017
Assignees:
The Chemo-Sero-Therapeutic Research Institute, Jectas Innovators Company Limited
Abstract: The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The EDS vaccine provided to this end contains as an active ingredient fused protein in which a polypeptide having a coiled-coil forming unit is bound to the knob region in the fiber protein of EDS virus (EDSV).
Type:
Application
Filed:
March 16, 2015
Publication date:
February 16, 2017
Applicants:
The Chemo-Sero-Therapeutic Research Institute, Jectas Innovators Company Limited
Abstract: A purpose is to provide a vaccine which can prevent porcine edema disease in farms where porcine edema disease is anticipated. Meeting this purpose is a vaccine that is a fusion protein in which Stx2eB and a polypeptide having a coiled-coil forming unit are joined or a multimer of the fusion protein, and by immunizing pigs with this vaccine, it is possible to induce potent neutralizing antibodies and to defend against the onset of porcine edema disease.
Type:
Application
Filed:
October 18, 2013
Publication date:
December 17, 2015
Applicants:
The-Chemo-Sero-Therapeutic Research Institute, Jectas Innovators Company Limited