Abstract: Vaccines capable of eliciting an immune antitumor response for prostate tumors are disclosed. The active ingredient in such vaccines is selected from the group consisting of human PSA and expression system capable of generating in situ human PSA.
Abstract: Depending on the antigen encapsulated, liposomal formulations are subject to instability in the presence of alum. Formulations containing a nonionic detergent as a stabilizing agent avoid this instability.
Type:
Grant
Filed:
June 7, 1995
Date of Patent:
October 13, 1998
Assignees:
The United States of America as represented by the Secretary of the Army, Jenner Technologies
Abstract: Antitumor vaccine compositions and methods for treating tumors that express the GA733-2 antigen are disclosed. The vaccines comprise a GS733-2 antigen in a liposomal carrier.