Abstract: The invention discloses a promoter which can be induced to express in acidic conditions, and relates to the field of bioengineering technology. The promoters of the invention are separated from A. niger and can actuate and/or regulate the expression of the effectively connected nucleic acids in A. niger. In the invention the expression of the promoters is studied in A. niger, and it is indicated that some promoters show weak expression, and some show strong activity. The invention provides an effective method and new thought for organic acids production by fungi or other products produced by fermentation under acidic conditions.
Type:
Grant
Filed:
November 11, 2016
Date of Patent:
March 27, 2018
Assignee:
Jiangnan Unviersity
Inventors:
Long Liu, Jian Chen, Guocheng Du, Xian Yin, Jianghua Li