Abstract: The present invention discloses an aralkyl substituted piperidine or piperazine derivative and the use of the derivative in preparation of medicaments for treating schizophrenia and correlative psychoneuroses. It is shown by pharmacological tests that the derivative of the present invention has better antischizophrenic effect and less toxicity. Said derivative is a free base or salt of the compound having the following general formula.
Type:
Application
Filed:
July 28, 2008
Publication date:
June 30, 2011
Applicants:
JIANGSU GOWORTH INVESTMENT CO. LTD., SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
Inventors:
Jianqi Li, Shaoping Peng, Wangping Cai, Kai Gao
Abstract: The present invention relates to an aralkyl alcohol piperidine derivative and use as antidepressant thereo. The said aralkyl alcohol piperidine derivative has a triple inhibition effect on the reuptaking of 5-HT, NA and DA. The derivative may be administered to the patient in need of such treatment in the form of composition by oral administration, injection and the like.
Type:
Application
Filed:
June 8, 2009
Publication date:
June 30, 2011
Applicants:
JIANGSU GOWORTH INVESTMENT CO. LTD, SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
Inventors:
Jianqi Li, Kai Gao, Wangping Cai, Yongyong Zheng
Abstract: The present invention discloses a group of histone deacetylase inhibitors and use thereof. The histone deacetylase inhibitors are useful in the treatment of malignant tumors and the diseases associated with differentiation and proliferation.
Type:
Application
Filed:
June 9, 2009
Publication date:
June 23, 2011
Applicants:
JIANGSU GOWORTH INVESTMENT CO. LTD, SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
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