Patents Assigned to Jiangsu Hengrui Medicine Company Ltd.
  • Patent number: 7112605
    Abstract: The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1–C6-alkyl, cyclopentyl, cyclohexyl, C1–C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; R2 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1–C6-alkyl, cyclopentyl, cyclohexyl, C1–C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; and R3 is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, c-propyl, n-butyl, isobutyl; provided that when R1 is a methylsulfonyl or aminosulfonyl group, R2 is any group as defined above except a methylsulfonyl or aminosulfonyl group; and when R2 is a methylsulfonyl or aminosulfonyl group, R1 is any group as defined above except a methylsulfonyl or aminosulfonyl group, also to processes for the preparation of such compounds, to pharmaceutical co
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: September 26, 2006
    Assignees: Research Institute of Materia Medica Chinese Acadamy of Medical Sciences, Jiangsu Hengrui Medicine Company Ltd.
    Inventors: Zongru Guo, Guifang Cheng, Fengming Chu, Ai Ping Bai, Wen Hui Hu, Fang Shen, Guangzhong Yang, Boling Xu
  • Publication number: 20040029951
    Abstract: The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) 1
    Type: Application
    Filed: May 14, 2003
    Publication date: February 12, 2004
    Applicants: Research Institute of Material Medica, Chinese Academy of Medical Sciences;, Jiangsu Hengrui Medicine Company Ltd.
    Inventors: Zongru Guo, Guifang Cheng, Fengming Chu