Abstract: A bakuchiol derivative, a pharmaceutically acceptable salt thereof, and a preparation method and use of the same. The bakuchiol derivative has a structure shown in formula (I): The above series of amphiphilic antibacterial compounds based on bakuchiol have comparatively excellent antibacterial activities and can overcome the generation of drug resistance of bacteria in drug resistance research simulated in a laboratory.
Type:
Grant
Filed:
October 30, 2020
Date of Patent:
February 27, 2024
Assignee:
JIANGXI SHIMEI PHARMACEUTICAL CO., LTD
Inventors:
Shuimu Lin, Shouping Liu, Hongxia Li, Hong Jiang
Abstract: A bakuchiol derivative, a pharmaceutically acceptable salt thereof, and a preparation method and use of the same. The bakuchiol derivative has a structure shown in formula (I): The above series of amphiphilic antibacterial compounds based on bakuchiol have comparatively excellent antibacterial activities and can overcome the generation of drug resistance of bacteria in drug resistance research simulated in a laboratory.