Patents Assigned to JIANGXI SYNERGY PHARMACEUTICAL CO., LTD
  • Method for preparing Crisaborole
    Patent number: 11214581
    Abstract: The invention relates to a method for preparing Crisaborole of Formula I, comprising using m-methylphenol as the starting material to obtain a target product through a five-step reaction. The starting materials and the raw materials used in each step of the method according to the present invention are cheap and easy to obtain, and the process is simple. The reaction of introducing boron atoms into the benzene ring to form an oxygen boron heterocycle is novel, with high yield and mild conditions, and is suitable for industrial production.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: January 4, 2022
    Assignee: JIANGXI SYNERGY PHARMACEUTICAL CO., LTD
    Inventors: Zhengwei Pang, Siming Ye, Yang Liu, Weiping Huang, Liyong Zhou, Yujie Feng