Abstract: A specific target-oriented social media tweet sentiment analysis method includes: preprocessing social media tweet data to obtain a target text and a specific target; passing the target text and the specific target through an embedding layer to obtain target text word vectors and obtain a specific target word vector, respectively; passing the target text word vectors through a self-attention structure to obtain a self-attention result; combining the self-attention result with the specific target word vector and passing through a cross-attention structure to obtain cross-attention results; concatenating the cross-attention results to obtain an attention representation matrix; and passing the attention representation matrix through a pooling layer, a fully connected layer and a softmax layer to obtain a sentiment tendency of the specific target.

Abstract: The present disclosure provides a class of Pyridopyrimidine compounds having a structure shown in Formula (I) or their pharmaceutically acceptable salts, or stereoisomers or prodrug molecules and applications thereof. The compounds in the present disclosure can efficiently and selectively degrade AKT3 protein in cells without affecting AKT1/2, thereby significantly inhibiting tumor cell proliferation mediated by high expression of AKT3 protein. It can be used to prepare therapeutic drugs for cancer and other diseases related to abnormal expression of AKT3 protein.

Abstract: Disclosed are a neural network model update method and device, and a computer storage medium. The method includes: randomly generating a preset number of sub-neural network models as nodes in a blockchain; using a ring signature to share a local data set in the blockchain, and uniformly dividing a data set in the blockchain to generate a training set and a test set; training each node through the training set to generate a trained model, packaging the trained model as a model transaction and sharing the model transaction in the blockchain; using the test set selected by voting to test the model transaction and generating a test result; when the test result is greater than a benchmark evaluation, taking the sub-neural network model corresponding to the test result as a valid vote; and voting a previous block corresponding to the valid vote, selecting a consistent block, and updating all nodes.

Abstract: An in-situ and in-operando internal state detecting system for an energy storage device comprises a first acoustic signal-emitting acoustic signal emission module, an interior-residing optical sensing module, and a first input optical signal-providing signal demodulation module. The optical sensing module receives a second acoustic signal when the first acoustic signal transmits inside the energy storage device, and outputs a first optical signal, which is demodulated and analyzed by the signal demodulation module to obtain acoustic feature information. Optionally, the signal demodulation module also provides a second input optical signal, and the optical sensing module outputs a second optical signal, which is analyzed by the signal demodulation modulation module to obtain optical feature information.

Abstract: The present disclosure provides a chitosan-modified opto-hydrodynamic micromotor and a preparation method and use thereof, and belongs to the technical field of micromotors. The chitosan-modified opto-hydrodynamic micromotor provided by the present disclosure is composed of Phaeodactylum tricornutum Bohlin and a chitosan solution. The chitosan-modified opto-hydrodynamic micromotor provided by the present disclosure has high biocompatibility, can non-invasively remove biological threats in a microenvironment containing cells with a sterilization rate reaching about 98%, and can achieve high-efficiency sterilization without affecting cell viability.

Abstract: Disclosed is a method for constructing an auditable and privacy-preserving collaborative deep learning platform based on a blockchain-empowered incentive mechanism, which allows trainers of multiple similar models to cooperate for training deep learning models while protecting confidentiality and auditing correctness of shared parameters. The invention has the following technical effects. Firstly, the encryption method used by model trainers protects the confidentiality of sharing parameters; furthermore, the updated parameters are decrypted through the cooperation of all participants, which reduces the possible disclosure of parameters. Secondly, the encrypted parameters are stored in the blockchain, and are only available to participants and authorized miners who are responsible to update parameters.

Abstract: A respirator for measuring a respiratory rate of a biofilm includes a body, a carbon dioxide absorption tube and a perforated partition disposed in an interior of the body. The perforated partition divides the interior of the body into an oxygen mass-transfer stir zone including a stirring device and a biofilm reaction zone for placing MBBR fillers. The carbon dioxide absorption tube includes an air vent and contains a solution capable of absorbing CO2. The perforated partition has a first hole corresponding to a middle portion and a lower portion of the perforated partition and acting as a liquid-exchange channel, and a second hole corresponding to an upper portion of the perforated partition and acting as a gas-exchange channel, and the oxygen mass-transfer stir zone is communicated with the biofilm reaction zone through the liquid-exchange channel and the gas-exchange channel.

Abstract: The present disclosure provides a class of 2-aminopyrimidine compounds with a structure shown in Formula (I) or their pharmaceutically acceptable salts, isotope derivatives, solvates, or their stereoisomers, geometric isomers, tautomers, or prodrug molecules or metabolites and pharmaceutical compositions and application thereof. The compounds of the present disclosure can efficiently and selectively inhibit the kinase activity of Janus Kinase 3 (JAK3), and have strong signal inhibition and cell proliferation inhibition effects on various blood tumor cells (especially human acute myeloid leukemia cell U937 cells) and solid tumor cells. They can be used to prepare anti-tumor drugs and drugs for preventing and treating inflammatory diseases.

Abstract: A dual-pulse excitation method for ultra-fast, super-resolution all-optical magnetic recording includes the steps of: providing a first excitation pulse and a second modulation pulse; and focusing the first excitation pulse and the second modulation pulse, and then radiating the two pulses in sequence to a magneto-optical recording medium, so that an area of the magneto-optical recording medium irradiated undergoes opto-magnetic reversal. By controlling the time delay, spatial overlapping area, and energy density ratio between the dual femtosecond laser pulses, it can induce a second reversal of the magnetization field in the spatial overlapping area of the two pulses on the magneto-optical material that can achieve single-pulse opto-magnetic reversal to obtain all-optical magnetic recording beyond the diffraction limit. This process takes place within several hundred picoseconds, thus providing an effective technical means for ultra-high density and ultra-fast magnetic storage.

Abstract: Disclosed is a method for constructing an emergency reporting system of vehicle networking based on multi-signatures, which comprises the following steps: initializing an emergency reporting system to obtain a public-private key pair and pre-calculation parameters of a vehicle set; obtaining authentication information of the emergency based on the public-private key pair and the pre-calculation parameters; integrating the authentication information to obtain multi-signatures of the emergency; and completing the system construction by regulating a traffic state based on the multi-signatures. The method realizes the efficient signature generation function of the vehicle with limited computing resources, reduces the communication pressure and computing pressure of roadside units, and may effectively prevent the common rogue key attacks in other schemes.

Abstract: A method and system for in operando, in situ, and real-time monitoring the state of an electrochemical device, e.g. battery, is provided, which is by means of an optical fiber probe inside the electrochemical device. The method includes: shedding an input light into the optical fiber probe and detecting an output light transmitted therefrom; and determining state of health of the electrochemical device based on the output light. The determination step can be based on a change of the refractive index or of the cladding mode or the surface plasmon resonance, all derived from the output light, in the instant state compared to a prior state. The method can simultaneously detect other parameters including state of charge, temperature, pressure, strain, displacement, vibration, or gas release inside the electrochemical device. With a core mode for correction, the determination of these parameters can also realize a high accuracy.

Abstract: A temperature-sensitive hydrogel material combination, a preparation method thereof, and use thereof are provided. The temperature-sensitive gel material combination provided by the present invention includes an SDF-1-loaded chitosan-hyaluronic acid solution and an Apt19S-loaded chitosan-hyaluronic acid solution. The present invention aims to develop a temperature-sensitive injectable double-layer hydrogel loaded with biological factors capable of promoting cell migration, which is used for promoting the regeneration of periodontal tissues.

Abstract: A text sentiment analysis method based on multi-level graph pooling includes steps of: preprocessing a target text; taking collocate point mutual information between word nodes as an edge weight between the word nodes, and building a graph for each text independently; constructing a multi-level graph pooling model, of which a gated graph neural network layer transfers low-level information, a first graph self-attention pooling layer performs an initial graph pooling operation and uses a Readout function to extract low-level features, a second graph self-attention pooling layer performs a graph pooling operation again, performs a pruning update on the graph structure by calculating attention scores of nodes in the graph and uses a Readout function to extract high-level features; obtaining a multi-level final vector representation through a feature fusion function; and selecting a sentiment category corresponding to a maximum probability value as a final sentiment category output of the text.

Abstract: With the popularity of Blockchain comes grave security-related concerns. Achieving privacy and traceability simultaneously remains an open question. Efforts have been made to address the issues, while they may subject to specific scenarios. The present disclosure proposes a method, a system, and a device for maintaining privacy and traceability of a Blockchain-based system. The method includes: registering in a Blockchain-based system; transmitting a message from a transmitter T to a receiver R via an anonymous network, after a registration request of the transmitter T has been approved and storing message transmission data generated during a message transmission process in a Blockchain; and performing an identity disclosure by using the message transmission data when the message is detected to be false. The anonymous network may transmit the message by onion routing. The solution proposed by the present disclosure can achieve traceability and privacy for a Blockchain-based system simultaneously.

Abstract: A social recommendation method based on a multi-feature heterogeneous graph neural network is provided and includes: extracting attribute information of users and topics to code; processing user coding information and topic coding information through a multi-layer perceptron to obtain initial feature vectors of the users and the topics; establishing a heterogeneous graph by taking the users and the topics as nodes; inputting the heterogeneous graph into a heterogeneous graph neural network to perform information transmission in combination with an attention mechanism, and updating the feature vectors; and performing similarity calculation on the feature vectors of the users, and selecting the user and the topic with the highest similarity with the feature vector of the user for recommendation. Social information can be mined more comprehensively, features of users and interested topics of the users can be deeply fused, and recommendation accuracy and user experience can be improved.

Abstract: The invention discloses a microlens and an application thereof, wherein the microlens is a lipid particle. The microlens prepared by the invention is simple in preparation and extraction methods, and does not need extra processing. The lipid particle is capable of serving as an optical element inside a cell to exert an optical function and has a complete biocompatibility; and meanwhile, the lipid particle is naturally generated inside the cell, and has a natural position-close relationship with a microstructure inside the cell, and is capable of collecting and re-positioning an optical signal of the microstructure in a near field, so that an imaging quality of the cell microstructure of an optical microscope is effectively improved.

Abstract: An electrode material, its manufacturing method, and its use as a cathode material in batteries are provided. The electrode material comprises a plurality of nanoparticles, each having a diameter of approximately 100-400 nm and comprising a core and a shell encapsulating the core. The shell comprises carbon and nitrogen, respectively having a mass fraction of approximately 70-90% and approximately 5-20% relative to a total mass of the shell. The core comprises sulfur, having a mass fraction of approximately 40-97% relative to a total mass of the core. The core has a mass fraction of approximately 50-90% relative to a total mass of each nanoparticle. The electrode material can be used in a cathode of a Li—S battery, which has a good energy storage capacity, a high electrochemical stability, and a low capacity decay.

Abstract: A fiber-optic sensing apparatus is provided, including an outer sleeve, an optical fiber sensor arranged within the outer sleeve, and a filling medium. The optical fiber sensor is capable of detecting a change of a refractive index or a change of surface plasmon waves over an outer surface of the outer sleeve. The filling medium may have a matching refractive index with the outer sleeve and with the optical fiber sensor. The outer sleeve may be exposed directly to the outside medium, or may be coated with at least one functional film layer such as a surface plasmon resonance (SPR)-active base film layer, or a reactive film layer that is reactive to a target molecule in the outside medium.

Abstract: The present disclosure discloses a polarization-maintaining hollow-core antiresonant fiber. An inner layer of the polarization-maintaining hollow-core antiresonant fiber includes first thin walls, second thin walls, and third thin walls. The present disclosure introduces high birefringence through the wall thickness difference between the first thin wall and the second thin wall, and effectively amplifies a birefringence effect achieved by the wall thickness difference through quasi multi-symmetric structures of the first thin walls and the second thin walls. In addition, the present disclosure reduces the transmission loss and suppresses the leakage of light through the inner layer, particularly, the third thin walls of the inner layer, so that the fiber of the present disclosure realizes polarization maintaining, and meanwhile, reduce the loss as far as possible.

Abstract: A fiber-optic sensing apparatus, system, and method for characterizing at least one metal ion in a solution are provided. The sensing apparatus includes a fiber-optic sensor and a controller. The sensor includes an optical fiber with tilted grating in its core, and includes a conductive and surface plasmon resonance (SPR)-active coating assembly that allows the sensor to also serve as an electrochemical working electrode. The controller is electrically connected with the sensor, configured to provide an adjustable potential such that when the coating assembly is in contact with the solution, redox reactions of each of the at least one metal ion occur on an outer surface thereof, resulting in a detectable change of the surface plasmon waves generated in the fiber-optic sensor. Based on the change thus detected, identities and/or concentration of the at least one metal ion in the solution can be determined with high accuracy and sensitivity.