Patents Assigned to John S. Nagle
  • Patent number: 6034091
    Abstract: Disclosed herein is a method for treating depression associated with alcoholism in a patient comprising administering to the patient a pharmacologically effective dose of an opioid antagonist, and a pharmacologically effective dose of at least one drug compound selected from the group consisting of a tricyclic antidepressant, an a-typical antidepressant, and lithium.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: March 7, 2000
    Assignee: John S. Nagle
    Inventor: Lee G. Dante
  • Patent number: 5856332
    Abstract: A new composition and method for treating depression is claimed comprising administering to a patient exhibiting said illness or illnesses a pharmacologically effective dose of an opioid antagonist having a pentacyclic nucleus, and a pharmacologically effective dose of a tricyclic antidepressant.
    Type: Grant
    Filed: August 28, 1996
    Date of Patent: January 5, 1999
    Assignee: John S. Nagle, Esq.
    Inventor: Lee G. Dante
  • Patent number: 5817665
    Abstract: This invention relates to a composition and method for treating depression by administering to a patient a pharmacologically effective dose of an opioid antagonist having a pentacyclic nucleus structurally analogous to naltrexone, and a pharmacologically effective dose of a nontricyclic antidepressant
    Type: Grant
    Filed: November 20, 1995
    Date of Patent: October 6, 1998
    Assignee: John S. Nagle
    Inventor: Lee G. Dante
  • Patent number: 5512593
    Abstract: A new composition and method of treating depression includes administering to a depressed patient a pharmacologically effective dose of naloxone or naltrexone or their pharmacologically effective salts and esters in combination with at least one nontricyclic serotonin reuptake inhibitor antidepressant or their pharmacologically effective salts and esters. The patient may while undergoing antidepressant therapy be undergoing treatment with a benzodiazepine for anxiety.
    Type: Grant
    Filed: March 2, 1993
    Date of Patent: April 30, 1996
    Assignee: John S. Nagle
    Inventor: Lee G. Dante