Abstract: In one embodiment of the invention, a method for a minimally invasive surgical system is disclosed. The method includes capturing and displaying camera images of a surgical site on at least one display device at a surgeon console; switching out of a following mode and into a masters-as-mice (MaM) mode; overlaying a graphical user interface (GUI) including an interactive graphical object onto the camera images; and rendering a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.
Type:
Application
Filed:
February 25, 2013
Publication date:
September 19, 2013
Applicants:
The Johns Hopkins University c/o John Hopkins Technology Transfer, Intuitive Surgical Operations, Inc.
Inventors:
Simon P. DiMaio, Christopher J. Hasser, Russell H. Taylor, David Q. Larkin, Peter Kazanzides, Anton Deguet, Balazs Peter Vagvolgyi, Joshua Leven
Abstract: The present invention relates to novel boronic chalcone derivatives which are useful as antitumor/anticancer agents. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good inhibitors of the growth of human breast cancer cells. The present invention also relates to the use of the novel boronic chalcone derivatives to treat cancer. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of cancer.
Type:
Grant
Filed:
June 12, 2003
Date of Patent:
April 7, 2009
Assignees:
Johns Hopkins University, Johns Hopkins Technology Transfer
Abstract: In one embodiment of the invention, a method for a minimally invasive surgical system is disclosed. The method includes capturing and displaying camera images of a surgical site on at least one display device at a surgeon console; switching out of a following mode and into a masters-as-mice (MaM) mode; overlaying a graphical user interface (GUI) including an interactive graphical object onto the camera images; and rendering a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.
Type:
Application
Filed:
August 11, 2008
Publication date:
February 5, 2009
Applicants:
Intuitive Surgical, Inc., The Johns Hopkins University c/o Johns Hopkins Technology Transfer
Inventors:
Simon P. DiMaio, Christopher J. Hasser, Russell H. Taylor, David Q. Larkin, Peter Kazanzides, Anton Deguet, Balazs Peter Vagvolgyi, Joshua Leven
Abstract: The present invention provides a role for neurotrophins in hES cell survival and important new insights into the molecular mechanisms controlling the growth of these cells. Although previous studies identified growth factors that affect self-renewal of hES cells, the novelty of the present invention is the identification of factors that act through specific receptors present on hES cells and activate the receptors at physiological concentrations to promote survival and proliferation.
Type:
Application
Filed:
December 30, 2005
Publication date:
October 23, 2008
Applicant:
The Johns Hopkins University Johns Hopkins Technology Transfer
Inventors:
Peter J. Donovan, April D. Pyle, Leslie F. Lock
Abstract: The present invention relates to novel boronic acid aryl derivatives which are useful as antitumor/anticancer agents. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good inhibitors of the growth of human breast cancer cells. The present invention also relates to the use of the novel boronic acid aryl derivatives to treat cancer. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of cancer.
Type:
Application
Filed:
December 21, 2004
Publication date:
July 17, 2008
Applicant:
John Hopkins University, Johns Hopkins Technology Transfer