Abstract: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.

Abstract: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injecfion sequence is complete.

Abstract: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.

Abstract: The present invention is directed to the diagnosis and assessment of wound status by quantitating levels of cortisol present in wound fluid. The present invention is also directed to a kit and test strip for assessing wound status.

Abstract: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.

Abstract: The invention relates to a catheter and a method of placing a catheter that includes a substantially tubular body portion having an outside diameter no less than the inside diameter of an opening in a catheter introducer adapted to insert a portion of the catheter into a patient's body. The catheter also includes a transition member portion adjacent to a first end of the tubular body portion. The transition member portion has an outside diameter that is less than the outside diameter of the tubular body portion and less than the inside diameter of the opening in the catheter introducer. The invention contemplates that the transition member can be coupled to the end of the tubular body portion, integrally formed with the body portion, or extends from the end of body portion and be removable from a distal end of the body portion.

Abstract: The invention provides a method of preparing water-insoluble polysaccharide sponges, and sponges obtained by means of the method. The method comprises: (a) providing an aqueous solution of a soluble polysaccharide; (b) freezing the solution; (c) treating the frozen solution with a water-miscible organic solvent such as isopropanol to effect solvent exchange for the water in the frozen solution; and (d) drying the resulting polysaccharide material. The organic solvent contains a cross-linking agent such as calcium chloride to render the polysaccharide water-insoluble in the solvent-exchange step (c). The resulting materials are more conformable and less friable than freeze-dried polysaccharide sponges.

Abstract: A method for delivering liquids is disclosed wherein a quantity of the liquid is provided within a cell within a cassette. The cassette is received within a sleeve having an open end. A flap at the open end of the sleeve extends inwardly through the open end between the sleeve and cassette to abut a lip on the cassette and hold the cassette therein. Impingement of the flap pushes the flap away from the lip to allow the cassette to move out of the sleeve. A label mounted within the sleeve rotates between a viewable position where it is visible through a window in the sleeve and a retracted position away from the window. Extraction and reinsertion of the cassette into the sleeve moves the label from the viewable to the nonviewable position.

Abstract: A safety cover, which securably and reliably prevents the readvancement of the tip of a cannula once it has been retracted thereinto, is designed having an elongate body which includes an axial channel having elements which displace and block linear passage of the cannula once it has been retracted. In a first embodiment the displacing elements are inwardly and rearwardly extending bristles which provide for unidirectional motion of the cannula relative to the safety cover, thereby locking the cannula once it has been retracted. In a second embodiment, the displacing element is the axial channel itself which has a curvate bias and distorts into a non-linear path once the cannula is retracted. In a third embodiment, the displacing element is a spring plate which, when compressed permits the cannula to pass through, but once the cannula has been retracted, expands to prevent the tip from being readvanced.

Abstract: An apparatus and process for hydrogen peroxide vapor sterilization of medical instruments and similar devices make use of hydrogen peroxide vapor released from a substantially non-aqueous organic hydrogen peroxide complex, such as a urea-peroxide complex. Optionally, a plasma can be used in conjunction with the vapor. A method for preparing substantially non-aqueous hydrogen peroxide complexes is also provided. These complexes are useful as a source of peroxide vapor in hydrogen peroxide vapor sterilizers and as a component of self-sterilizing packaging materials.

Abstract: In a flexible endoscope having a flexible insertion tube comprising a tubular, biocompatible elastomeric outer covering thereabout which encloses an interior space, the improvement according to the present invention comprises a vapor barrier between the outer covering and the interior space. Thus, vapor, such as hydrogen peroxide or other sterilants, passing through the outer covering from an atmosphere thereabout is prevented from entering the interior space by the vapor barrier. Further, the vapor is thus prevented from interacting with substances, such as lubricants, within the interior space to produce agents harmful to the elastomeric covering.

Abstract: An apparatus and method for vapor sterilization of articles such as medical devices and instruments with lumens. The lumens are connected in a sterilization chamber to a conduit which leads to an exhaust flow restrictor, which exhausts to a vacuum pump. The exhaust flow restrictor has a bypass also which exhausts to the vacuum pump. The majority of the gas from the sterilization chamber flows through the bypass on the exhaust flow restrictor while only a portion of the gas flows through the lumen. Because most of the gas flows through the bypass rather than through the lumens, the sterilization chamber can be pumped down rapidly. The attached lumens are sterilized effectively in spite of the rapid pumpdown rate.

Abstract: Absorbable implant materials having controlled porosity are formed by a method comprising the steps of: providing a dispersion of a bioabsorbable polymer, such as collagen, in a first solvent, such as water; adding particles of a second material, e.g. frozen water droplets or ice particles to the dispersion; followed by freezing the dispersion to form a frozen dispersion having the particles embedded therein, and removing both the first solvent and the second material from the frozen dispersion by freeze-drying or solvent extraction to leave the porous implant material. The invention also encompasses the use of such implant materials for wound healing applications.

Abstract: Material that is to be used in wrapping medical items or in making gowns, drapes, and the like is treated with silicone to make it liquid repellent. The material, after being sterilized by an oxidizing plasma process, still retains its repellency.

Abstract: A catheter needle tip protector and a safety mechanism which provides fail/save protection to clinical personnel against the possibility of accidental punctures by a used intravenous (IV) needle through the provision of automatic catheter needle tip protecting structure which becomes operative upon withdrawal of the needle from the body of a patient.

Abstract: A method for sterilizing a device, includes the following steps: contacting the device with liquid sterilant outside or inside a sterilization chamber at a first pressure, placing the device in the chamber before or after the contacting step, and decreasing the pressure of the chamber to a second pressure below the vapor pressure of the liquid sterilant. At least the decrease in pressure below about the vapor pressure of the liquid sterilant occurs at a pumpdown rate of less than 0.8 liters per second, calculated based on the time required to evacuate the chamber from atmospheric pressure to 20 torr when the chamber is empty and dry.

Abstract: In a first process described a tapered catheter tip is molded by placing a tubular catheter over a mandrel and inserting the mandrel and catheter assembly into a mold having an inner mold surface. The molded catheter with flash is thereafter removed from the mold and the mandrel removed from the catheter. The catheter and flash are inserted into a jig which defines an opening through which the flash extends. The opening is defined by a cutting surface and the flash extends above such cutting surface. A cutter is then moved along the cutting surface in order to severe the flash at precisely the appropriate point along the catheter length to leave a formed trimmed catheter. The catheter is thereafter removed from the jig for further processing.

Abstract: A method for forming a glove in an elastomer deposition process employs a folded glove form. The form has a hand forming portion having palm and finger forming portions. The finger forming portions terminate in distal tips and the cuff forming portion terminates in a terminal end for forming the cuff opening. The form is folded so that finger forming portion distal tips and the cuff forming portion terminal end lie in separate planes and in facing relationship to one another. To form the glove, the form is vertically oriented and dipped into a bath of elastomer with both the cuff forming portion terminal end and the finger portion distal tips facing upwards.

Abstract: A sterilization system using a sterilization process monitoring device which is capable of indicating the efficacy of the sterilization process in an enclosed sterilization container while still maintaining the sealed state of the sterilization container. The process monitoring device comprises at least one biological indicator and/or at least one chemical indicator. Upon completion of the sterilization cycle, the process monitoring device can be advantageously removed from the system to determine chemical and/or biological efficacy of the sterilization process. The removal of the biological and/or chemical indicators does not disturb the sterilized state of the articles inside the sterilization container.