Abstract: After forming a first electromagnetic radiation blocking layer over a front side of a device wafer, the device wafer is bonded to a handle substrate from the front side. A semiconductor substrate in the device wafer is thinned from its backside. Trenches are formed extending through the device wafer and the first electromagnetic radiation blocking layer such that the device wafer is singulated into semiconductor dies. A second electromagnetic radiation blocking layer portion is formed on a backside surface of and sidewalls surfaces of each of the semiconductor dies such that each of the semiconductor dies are fully encapsulated by the first and second electromagnetic radiation blocking layer portions.

Abstract: The present invention relates generally to an intraocular lens system controlled with a processor, including a liquid meniscus lens and supporting electronics. Embodiments may include intraocular lens systems of various shapes and sizes, liquid meniscus lens components of various shapes and sizes, variations in supporting electronics with corresponding variations in lens function.

Abstract: Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.

Abstract: A method for estimating and tracking refractive error progression of an individual includes estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual's age by comparison to a reference population; estimating an expected SPHEQ trajectory over a future predetermined period of time; comparing the expected SPHEQ trajectory with the reference population; and comparing the expected SPHEQ trajectory with an expected SPHEQ trajectory using an ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time.

Abstract: Methods and apparatus for sealing and encapsulating components on and within a multi-piece insert are set forth herein. In some embodiments, an ophthalmic lens is cast molded from a silicone hydrogel and the component includes a sealed and encapsulated multi-piece insert portion.

Abstract: An ophthalmic device having improved oxygen transmissibility is provided. The ophthalmic device includes a hydrogel lens wherein the peripheral zone of the hydrogel lens includes a plurality of raised portions on the surface of the lens proximal to the ocular surface.

Abstract: The present invention relates to silicone hydrogels having a desirable balance of properties which can be formed without diluents. The silicone hydrogels are formed from reactive mixtures comprising at least one hydroxyl substituted, monofunctional polydialkylsiloxane monomer having between 2 and 120 dialkylsiloxane repeating units, at least one slow reacting hydrophilic monomer and at least one hydroxyl containing hydrophilic monomer.

Abstract: Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.

Abstract: Contact lenses incorporate mask lens designs that at least one of slow, retard or preventing myopia progression. The lens includes a first zone at a center of the lens; at least one peripheral zone surrounding the center and having a dioptric power that is different than that at the center; and an opaque mask beginning at a radial distance from the center, thereby providing a lens power profile having substantially equivalent foveal vision correction to a single vision lens, and having a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some examples, the methods and apparatus to form the biocompatible energization elements involve forming cavities composing active cathode chemistry. The active elements of the cathode and anode are sealed with a biocompatible material. In some examples, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: The invention provides a package for storing medical devices that substantially eliminates elution of a pharmaceutical agent, from the device into the package. As well, a new lidstock is described for use with the package, which results in better retention of drug throughout the bowl and lidstock.

Abstract: The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature.

Abstract: Disclosed are in-line apparatuses, systems and methods for measuring a physical characteristic of a constant supply of an ophthalmic device, the apparatuses including: an interferometer; an automatic alignment system that positions the interferometer or ophthalmic device; and a central processing unit in communication with the automatic alignment system and receiving measurements from the interferometer. The in-line apparatus measures the desired physical dimensions of the ophthalmic device in real time. In-line systems, apparatuses and methods for measuring a physical characteristic of an ophthalmic device can include: a camera imaging an actual position of a feature of the ophthalmic device; a vibration resistant interferometer projecting a surface measurement beam having a wavelength that transmits through a beam splitter onto the ophthalmic device; and an automatic alignment system positioning the interferometer and the camera.

Abstract: The present invention provides a method of making a mask for patterning a three-dimensional substrate. A mandrel includes a form machined in a surface corresponding to a shape of the substrate. A layer of material is deposited in a first region of the form and a metal layer is deposited in a second region of the form. A portion of the mandrel is subsequently removed. The present invention also provides a method of patterning a three-dimensional substrate with a mask.

Abstract: Methods for manufacturing an ophthalmic lens with an insert using voxel-based lithography techniques, wherein at least a portion of one surface may be free-formed from a reactive mixture are set forth herein. An ophthalmic lens precursor may be formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of reactive mixture, wherein the control may be on a voxel by voxel basis.

Abstract: The present invention relates to a method of manufacturing a contact lens including the steps of: (i) adding reactive components to a mold, wherein the reactive components comprise (a) at least one hydroxy-containing silicone component having a weight average molecular weight from about 200 to about 15,000 g/mole and (b) at least one mono-ether terminated, mono-methacrylate terminated polyethylene glycol having a weight average molecular weight from about 200 to about 10,000 g/mole; (ii) curing the reactive components within the mold to form the contact lens; and (iii) removing the contact lens from said mold.

Abstract: Antennas and antenna mandrels or assemblies may be designed and configured to enable one of one- or two-way communication and/or power transfer with mechanical devices such as ophthalmic devices, including contact lenses. These antennas and antenna mandrels or assemblies may be utilized to transmit data from the mechanical devices to receive data from a transmitter, and/or inductively charge an electromechanical cell or the like incorporated into a mechanical device.

Abstract: A system controller for an ophthalmic lens comprising an electronic system which actuates a variable-focus optic is disclosed herein. The system controller is part of an electronic system incorporated into the ophthalmic lens. The electronic system includes one or more batteries or other power sources, power management circuitry, one or more sensors, clock generation circuitry, control algorithms and circuitry, and lens driver circuitry. The controller including multiple state machines configured as digital logic gates.