Patents Assigned to Johnson Matthey Public Limted Company
  • Pharmaceutical compositions comprising metal complexes
    Patent number: 5824673
    Abstract: New pharmaceutical compositions and pharmaceutical compositions comprising metal complexes have activity against diseases caused by or related to overproduction or localized high concentration of nitric oxide in the body.
    Type: Grant
    Filed: February 26, 1996
    Date of Patent: October 20, 1998
    Assignee: Johnson Matthey Public Limted Company
    Inventors: Michael J. Abrams, Simon P. Fricker, Barry A. Murrer, Owen J. Vaughan
  • Cyclic polyamines
    Patent number: 5698546
    Abstract: Linked polyamine cyclic compounds of general formula V--R--A--R'--W where V and W are independently cyclic polyamine moieties having from 9 to 32 ring members and 3 to 8 amine nitrogens and having either one or more aromatic rings fused thereto or a heteroatom other than nitrogen incorporated in the ring, A is an aliphatic or aromatic moiety and R and R' are each a linking chain, possess improved partition coefficients at biologically relevant pH compared to known compounds, and possess high anti-HIV activity.
    Type: Grant
    Filed: June 20, 1996
    Date of Patent: December 16, 1997
    Assignee: Johnson Matthey Public Limted Company
    Inventors: Gary J. Bridger, Sreenivasan Padmanabhan, Renato T. Skerlj