Abstract: The present invention provides a composition for improving skin conditions, containing the extracellular domain of human bone morphogenetic protein receptor 1a as an active ingredient. The present invention contains the extracellular domain of human bone morphogenetic protein receptor 1a as an active ingredient inside a nanoliposome comprising hydrogenated lecithin as a constituent component, and the particle size is 50-250 nm. The composition of the present invention reduces wrinkles and alleviates atopic dermatitis. In addition, the present invention provides a method for improving skin conditions, comprising the step of administering a composition containing the extracellular domain of human bone morphogenetic protein receptor 1a as an active ingredient to a subject.
Type:
Application
Filed:
August 30, 2012
Publication date:
November 13, 2014
Applicant:
JOINT CENTER FOR BIOSCEINCES
Inventors:
Zung Yoon Yang, Byung Hak Yoon, Seung-Hyon Choi